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Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells.
Abdul-Wahid, Aws; Cydzik, Marzena; Fischer, Nicholas W; Prodeus, Aaron; Shively, John E; Martel, Anne; Alminawi, Samira; Ghorab, Zeina; Berinstein, Neil L; Gariépy, Jean.
Afiliación
  • Abdul-Wahid A; Departments of Medical Biophysics and Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada.
  • Cydzik M; Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
  • Fischer NW; Departments of Medical Biophysics and Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada.
  • Prodeus A; Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
  • Shively JE; Departments of Medical Biophysics and Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada.
  • Martel A; Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
  • Alminawi S; Departments of Medical Biophysics and Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada.
  • Ghorab Z; Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
  • Berinstein NL; Department of Immunology, Beckman Research Institute, City of Hope, Duarte, CA.
  • Gariépy J; Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Int J Cancer ; 143(8): 1963-1977, 2018 10 15.
Article en En | MEDLINE | ID: mdl-29756328
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Texto completo: 1 Colección: 01-internacional Asunto principal: Antígeno Carcinoembrionario / Matriz Extracelular / Fibroblastos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Int J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Antígeno Carcinoembrionario / Matriz Extracelular / Fibroblastos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Int J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Canadá