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Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein.
de Wispelaere, Melissanne; Lian, Wenlong; Potisopon, Supanee; Li, Pi-Chun; Jang, Jaebong; Ficarro, Scott B; Clark, Margaret J; Zhu, Xuling; Kaplan, Jenifer B; Pitts, Jared D; Wales, Thomas E; Wang, Jinhua; Engen, John R; Marto, Jarrod A; Gray, Nathanael S; Yang, Priscilla L.
Afiliación
  • de Wispelaere M; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Lian W; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Potisopon S; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Li PC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA.
  • Jang J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA.
  • Ficarro SB; Department of Cancer Biology, Department of Oncologic Pathology, Blais Proteomics Center, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, 45 Francis Street, Boston, MA 02115, USA.
  • Clark MJ; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Zhu X; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Kaplan JB; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Pitts JD; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
  • Wang J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA.
  • Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
  • Marto JA; Department of Cancer Biology, Department of Oncologic Pathology, Blais Proteomics Center, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, 45 Francis Street, Boston, MA 02115, USA.
  • Gray NS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02215, USA.
  • Yang PL; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: priscilla_yang@hms.harvard.edu.
Cell Chem Biol ; 25(8): 1006-1016.e8, 2018 08 16.
Article en En | MEDLINE | ID: mdl-29937406

Texto completo: 1 Colección: 01-internacional Asunto principal: Antivirales / Proteínas del Envoltorio Viral / Infecciones por Flavivirus / Internalización del Virus / Flavivirus Límite: Animals / Humans Idioma: En Revista: Cell Chem Biol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Asunto principal: Antivirales / Proteínas del Envoltorio Viral / Infecciones por Flavivirus / Internalización del Virus / Flavivirus Límite: Animals / Humans Idioma: En Revista: Cell Chem Biol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos