Activation of the Nrf2-ARE Pathway Ameliorates Hyperglycemia-Mediated Mitochondrial Dysfunction in Podocytes Partly Through Sirt1.

Zhang, Qunzi; Deng, Qiongxia; Zhang, Jun; Ke, JianTing; Zhu, Ye; Wen, Ruo Wei; Ye, Zengchun; Peng, Hui; Su, Zhong Zhen; Wang, Cheng; Lou, Tanqi

Zhang, Qunzi; Deng, Qiongxia; Zhang, Jun; Ke, JianTing; Zhu, Ye; Wen, Ruo Wei; Ye, Zengchun; Peng, Hui; Su, Zhong Zhen; Wang, Cheng; Lou, Tanqi.

Afiliación

Zhang Q; Division of Nephrology, Department of Medicine, the 5th Hospital of Sun Yat-sen University, Zhuhai, China.
Deng Q; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.
Zhang J; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.
Ke J; Division of Nephrology, Department of Medicine, the 5th Hospital of Sun Yat-sen University, Zhuhai, China.
Zhu Y; Division of Nephrology, Department of Medicine, the 5th Hospital of Sun Yat-sen University, Zhuhai, China.
Wen RW; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.
Ye Z; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.
Peng H; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.
Su ZZ; Department of Ultrasound, the 5th Hospital of Sun Yat-sen University, Zhuhai, China.
Wang C; Division of Nephrology, Department of Medicine, the 5th Hospital of Sun Yat-sen University, Zhuhai, China.
Lou T; Division of Nephrology, Department of Medicine, the 3rd Hospital of Sun Yat-sen University, Guangzhou, China.

Cell Physiol Biochem ; 48(1): 1-15, 2018.

Article en En | MEDLINE | ID: mdl-29996125

Asunto(s)

Mitocondrias/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; Sirtuina 1/metabolismo; Adenosina Trifosfato/metabolismo; Animales; Línea Celular; Creatinina/orina; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/patología; Glucosa/farmacología; Humanos; Hidroquinonas/farmacología; Hiperglucemia/metabolismo; Hiperglucemia/patología; Masculino; Proteínas de la Membrana/metabolismo; Ratones; Mitocondrias/efectos de los fármacos; Factor 2 Relacionado con NF-E2/antagonistas & inhibidores; Factor 2 Relacionado con NF-E2/genética; Podocitos/citología; Podocitos/efectos de los fármacos; Podocitos/metabolismo; Interferencia de ARN; ARN Interferente Pequeño/metabolismo; Transducción de Señal/efectos de los fármacos; Sirtuina 1/antagonistas & inhibidores; Sirtuina 1/genética; Superóxidos/metabolismo

Palabras clave

Antioxidant response element; Diabetes mellitus; Podocytes; Sirt1; Tert-butylhydroquinone

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Texto completo: 1 Colección: 01-internacional Asunto principal: Factor 2 Relacionado con NF-E2 / Sirtuina 1 / Mitocondrias Límite: Animals / Humans / Male Idioma: En Revista: Cell Physiol Biochem Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China

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