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Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIß.
Oviatt, Alexandria A; Kuriappan, Jissy A; Minniti, Elirosa; Vann, Kendra R; Onuorah, Princess; Minarini, Anna; De Vivo, Marco; Osheroff, Neil.
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  • Oviatt AA; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.
  • Kuriappan JA; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy.
  • Minniti E; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Vann KR; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.
  • Onuorah P; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.
  • Minarini A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • De Vivo M; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy. Electronic address: Marco.DeVivo@iit.it.
  • Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA; Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232-6307, USA; VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA. Electronic addr
Bioorg Med Chem Lett ; 28(17): 2961-2968, 2018 09 15.
Article en En | MEDLINE | ID: mdl-30006062
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Texto completo: 1 Colección: 01-internacional Asunto principal: Poliaminas / Etopósido / Inhibidores de Topoisomerasa II / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Poliaminas / Etopósido / Inhibidores de Topoisomerasa II / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos