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Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity.
Basler, Michael; Lindstrom, Michelle M; LaStant, Jacob J; Bradshaw, J Michael; Owens, Timothy D; Schmidt, Christian; Maurits, Elmer; Tsu, Christopher; Overkleeft, Herman S; Kirk, Christopher J; Langrish, Claire L; Groettrup, Marcus.
Afiliación
  • Basler M; Biotechnology Institute Thurgau (BITg) at the University of Konstanz, Kreuzlingen, Switzerland michael.basler@uni-konstanz.de marcus.groettrup@uni-konstanz.de.
  • Lindstrom MM; Division of Immunology, Department of Biology, University of Konstanz, Konstanz, Germany.
  • LaStant JJ; Principia Biopharma, South San Francisco, CA, USA.
  • Bradshaw JM; Principia Biopharma, South San Francisco, CA, USA.
  • Owens TD; Principia Biopharma, South San Francisco, CA, USA.
  • Schmidt C; Principia Biopharma, South San Francisco, CA, USA.
  • Maurits E; Division of Immunology, Department of Biology, University of Konstanz, Konstanz, Germany.
  • Tsu C; Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Konstanz, Germany.
  • Overkleeft HS; Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Kirk CJ; Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Langrish CL; Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Groettrup M; Kezar Life Sciences, South San Francisco, CA, USA.
EMBO Rep ; 19(12)2018 12.
Article en En | MEDLINE | ID: mdl-30279279
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Texto completo: 1 Colección: 01-internacional Asunto principal: Autoinmunidad / Subunidades de Proteína / Complejo de la Endopetidasa Proteasomal / Inhibidores de Proteasoma Límite: Animals Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Autoinmunidad / Subunidades de Proteína / Complejo de la Endopetidasa Proteasomal / Inhibidores de Proteasoma Límite: Animals Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article