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Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.
Ting, Pamela Y; Parker, Albert E; Lee, J Scott; Trussell, Chris; Sharif, Orzala; Luna, Fabio; Federe, Glenn; Barnes, S Whitney; Walker, John R; Vance, Julie; Gao, Mu-Yun; Klock, Heath E; Clarkson, Scott; Russ, Carsten; Miraglia, Loren J; Cooke, Michael P; Boitano, Anthony E; McNamara, Peter; Lamb, John; Schmedt, Christian; Snead, Jennifer L.
Afiliación
  • Ting PY; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Parker AE; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Lee JS; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Trussell C; Celgene, San Diego, CA, USA.
  • Sharif O; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Luna F; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Federe G; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Barnes SW; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Walker JR; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Vance J; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Gao MY; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Klock HE; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Clarkson S; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Russ C; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Miraglia LJ; Merck, Cambridge, MA, USA.
  • Cooke MP; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Boitano AE; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • McNamara P; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Lamb J; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Schmedt C; Magenta Therapeutics, Cambridge, MA, USA.
  • Snead JL; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
Nat Methods ; 15(11): 941-946, 2018 11.
Article en En | MEDLINE | ID: mdl-30297964

Texto completo: 1 Colección: 01-internacional Asunto principal: Células Madre Hematopoyéticas / Genoma Humano / ARN Guía de Kinetoplastida / Linfocitos T CD8-positivos / Sistemas CRISPR-Cas / Edición Génica / Proteína 9 Asociada a CRISPR Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Nat Methods Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Asunto principal: Células Madre Hematopoyéticas / Genoma Humano / ARN Guía de Kinetoplastida / Linfocitos T CD8-positivos / Sistemas CRISPR-Cas / Edición Génica / Proteína 9 Asociada a CRISPR Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Nat Methods Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos