Preservation of exosomes at room temperature using lyophilization.

Charoenviriyakul, Chonlada; Takahashi, Yuki; Nishikawa, Makiya; Takakura, Yoshinobu

Charoenviriyakul, Chonlada; Takahashi, Yuki; Nishikawa, Makiya; Takakura, Yoshinobu.

Afiliación

Charoenviriyakul C; Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Takahashi Y; Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address: ytakahashi@pharm.kyoto-u.ac.jp.
Nishikawa M; Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Takakura Y; Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

Int J Pharm ; 553(1-2): 1-7, 2018 Dec 20.

Article en En | MEDLINE | ID: mdl-30316791

Asunto(s)

Crioprotectores/química; Sistemas de Liberación de Medicamentos; Exosomas/química; Trehalosa/química; Animales; Copépodos/enzimología; ADN/genética; Electroforesis en Gel de Poliacrilamida; Excipientes/química; Liofilización; Luciferasas/farmacocinética; Luciferasas/farmacología; Masculino; Melanoma Experimental/metabolismo; Ratones; Ratones Endogámicos BALB C; ARN/genética; Temperatura; Factores de Tiempo

Palabras clave

Exosome; Freeze-drying; Lyophilization; Stability; Trehalose

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Texto completo: 1 Colección: 01-internacional Asunto principal: Trehalosa / Sistemas de Liberación de Medicamentos / Crioprotectores / Exosomas Límite: Animals Idioma: En Revista: Int J Pharm Año: 2018 Tipo del documento: Article País de afiliación: Japón

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