JS-K induces reactive oxygen species-dependent anti-cancer effects by targeting mitochondria respiratory chain complexes in gastric cancer.

Zhao, Xudong; Cai, Aizhen; Peng, Zheng; Liang, Wenquan; Xi, Hongqing; Li, Peiyu; Chen, Guozhu; Yu, Jiyun; Chen, Lin

Zhao, Xudong; Cai, Aizhen; Peng, Zheng; Liang, Wenquan; Xi, Hongqing; Li, Peiyu; Chen, Guozhu; Yu, Jiyun; Chen, Lin.

Afiliación

Zhao X; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Cai A; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Peng Z; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Liang W; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Xi H; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Li P; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Chen G; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, China.
Yu J; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, China.
Chen L; Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.

J Cell Mol Med ; 23(4): 2489-2504, 2019 04.

Article en En | MEDLINE | ID: mdl-30672108

Asunto(s)

Compuestos Azo/farmacología; Proliferación Celular/efectos de los fármacos; Donantes de Óxido Nítrico/farmacología; Piperazinas/farmacología; Neoplasias Gástricas/tratamiento farmacológico; Apoptosis/efectos de los fármacos; Catalasa/genética; Línea Celular Tumoral; Transporte de Electrón/efectos de los fármacos; Transporte de Electrón/genética; Humanos; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Mitocondrias/efectos de los fármacos; Mitocondrias/genética; Óxido Nítrico/genética; Especies Reactivas de Oxígeno/metabolismo; Neoplasias Gástricas/genética; Neoplasias Gástricas/patología; Superóxido Dismutasa-1/genética

Palabras clave

JS-K; apoptosis; gastric cancer; mitochondria respire chain complex; nitric oxide; reactive oxygen species

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Texto completo: 1 Colección: 01-internacional Asunto principal: Piperazinas / Neoplasias Gástricas / Compuestos Azo / Donantes de Óxido Nítrico / Proliferación Celular Límite: Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: China

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