SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension.

Mo, Xingbo; Zhang, Huan; Zhou, Zhengyuan; Zhu, Zhengbao; HuangFu, Xinfeng; Xu, Tan; Wang, Aili; Guo, Zhirong; Zhang, Yonghong

Mo, Xingbo; Zhang, Huan; Zhou, Zhengyuan; Zhu, Zhengbao; HuangFu, Xinfeng; Xu, Tan; Wang, Aili; Guo, Zhirong; Zhang, Yonghong.

Afiliación

Mo X; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, Jiangsu, People's Republic of China.
Zhang H; Department of Epidemiology, School of Public Health, Medical College of Soochow University, 199 Renai Road, Industrial Park District, Suzhou, 215123, Jiangsu, People's Republic of China.
Zhou Z; Center for Genetic Epidemiology and Genomics, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Zhu Z; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, Jiangsu, People's Republic of China.
HuangFu X; Department of Epidemiology, School of Public Health, Medical College of Soochow University, 199 Renai Road, Industrial Park District, Suzhou, 215123, Jiangsu, People's Republic of China.
Xu T; Changshu Center of Disease Control and Prevention, Suzhou, Jiangsu, People's Republic of China.
Wang A; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, Jiangsu, People's Republic of China.
Guo Z; Department of Epidemiology, School of Public Health, Medical College of Soochow University, 199 Renai Road, Industrial Park District, Suzhou, 215123, Jiangsu, People's Republic of China.
Zhang Y; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, Jiangsu, People's Republic of China.

Mol Biol Rep ; 46(2): 1617-1624, 2019 Apr.

Article en En | MEDLINE | ID: mdl-30689184

Asunto(s)

Proteínas Quinasas Activadas por AMP/genética; Hipertensión/genética; Proteínas Quinasas Activadas por AMP/metabolismo; Adulto; Anciano; Pueblo Asiatico/genética; China; Fumar Cigarrillos/efectos adversos; Fumar Cigarrillos/genética; Enfermedad de la Arteria Coronaria/genética; Etnicidad/genética; Femenino; Regulación de la Expresión Génica; Predisposición Genética a la Enfermedad; Estudio de Asociación del Genoma Completo; Genotipo; Humanos; Masculino; Persona de Mediana Edad; Polimorfismo de Nucleótido Simple/genética; Sitios de Carácter Cuantitativo; Factores Sexuales; Accidente Cerebrovascular/genética

Palabras clave

Gene expression; Genome-wide association study; Hypertension; PRKAG2

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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Quinasas Activadas por AMP / Hipertensión Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Mol Biol Rep Año: 2019 Tipo del documento: Article

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