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A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup.
Lancia, Carlo; Anninga, Jakob K; Sydes, Matthew R; Spitoni, Cristian; Whelan, Jeremy; Hogendoorn, Pancras C W; Gelderblom, Hans; Fiocco, Marta.
Afiliación
  • Lancia C; Mathematical Institute Leiden University, Niels Bohrweg 1, 2333 CA, Leiden, The Netherlands. c.lancia@math.leidenuniv.nl.
  • Anninga JK; Department Paediatric Oncology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
  • Sydes MR; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL and MRC London Hub for Trials Methodology Research, 90 High Holborn, London, WC1V 6LJ, UK.
  • Spitoni C; Mathematical Institute Utrecht University, Budapestlaan 6, 3584 CD, Utrecht, The Netherlands. c.spitoni@uu.nl.
  • Whelan J; Department of Epidemiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. c.spitoni@uu.nl.
  • Hogendoorn PCW; Department of Oncology, University College London Hospital, 235 Euston Rd, Fitzrovia, London, NW1 2BU, UK.
  • Gelderblom H; Department of Pathology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
  • Fiocco M; Department of Medical Oncology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Cancer Chemother Pharmacol ; 83(5): 951-962, 2019 05.
Article en En | MEDLINE | ID: mdl-30879111
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Óseas / Protocolos de Quimioterapia Combinada Antineoplásica / Osteosarcoma Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Chemother Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Óseas / Protocolos de Quimioterapia Combinada Antineoplásica / Osteosarcoma Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Chemother Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos