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Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment.
Wang, Lijun; Guo, Chuanlong; Li, Xiuxue; Yu, Xuemin; Li, Xiangqian; Xu, Kuo; Jiang, Bo; Jia, Xiaoling; Li, Chao; Shi, Dayong.
Afiliación
  • Wang L; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China. Electronic address: wanglijun@qdio.ac.cn.
  • Guo C; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Department of Pharmacy, College of Chemical Engineering, Qingdao Univer
  • Li X; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Yu X; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Qingdao, Shandong, 266000, China.
  • Li X; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Xu K; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Jiang B; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Jia X; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Li C; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China.
  • Shi D; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong, 266071, China; State Key Laboratory of Microbial Technology, Shandong University, Qing
Eur J Med Chem ; 177: 153-170, 2019 Sep 01.
Article en En | MEDLINE | ID: mdl-31132531
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Texto completo: 1 Colección: 01-internacional Asunto principal: Tiazoles / Factor 4E Eucariótico de Iniciación / Factor 4G Eucariótico de Iniciación / Hidrazonas / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Tiazoles / Factor 4E Eucariótico de Iniciación / Factor 4G Eucariótico de Iniciación / Hidrazonas / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article