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Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis.
Lopez Quezada, Landys; Li, Kelin; McDonald, Stacey L; Nguyen, Quyen; Perkowski, Andrew J; Pharr, Cameron W; Gold, Ben; Roberts, Julia; McAulay, Kathrine; Saito, Kohta; Somersan Karakaya, Selin; Javidnia, Prisca Elis; Porras de Francisco, Esther; Amieva, Manuel Marin; Di Az, Sara Palomo; Mendoza Losana, Alfonso; Zimmerman, Matthew; Liang, Hsin-Pin Ho; Zhang, Jun; Dartois, Veronique; Sans, Stéphanie; Lagrange, Sophie; Goullieux, Laurent; Roubert, Christine; Nathan, Carl; Aubé, Jeffrey.
Afiliación
  • Lopez Quezada L; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.
  • Li K; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.
  • McDonald SL; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.
  • Nguyen Q; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.
  • Perkowski AJ; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.
  • Pharr CW; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.
  • Gold B; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.
  • Roberts J; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.
  • McAulay K; Center for Global Health , Weill Cornell Medicine , 402 East 67th Street , New York , New York 10065 , United States.
  • Saito K; Les Centres GHESKIO , 33, Boulevard Harry Truman , Port-au-Prince , Haiti.
  • Somersan Karakaya S; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States.
  • Javidnia PE; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States.
  • Porras de Francisco E; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States.
  • Amieva MM; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain.
  • Di Az SP; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain.
  • Mendoza Losana A; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain.
  • Zimmerman M; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain.
  • Liang HH; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States.
  • Zhang J; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States.
  • Dartois V; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.
  • Sans S; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States.
  • Lagrange S; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France.
  • Goullieux L; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France.
  • Roubert C; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France.
  • Nathan C; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France.
  • Aubé J; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.
ACS Infect Dis ; 5(8): 1433-1445, 2019 08 09.
Article en En | MEDLINE | ID: mdl-31184461

Texto completo: 1 Colección: 01-internacional Asunto principal: Piridinas / Tionas / Cefalosporinas / Replicación del ADN / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: ACS Infect Dis Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Asunto principal: Piridinas / Tionas / Cefalosporinas / Replicación del ADN / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: ACS Infect Dis Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos