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Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.
Kang, Seong A; O'Neill, David J; Machl, Andreas W; Lumpkin, Casey J; Galda, Stephanie N; Sengupta, Shomit; Mahoney, Sarah J; Howell, Jessica J; Molz, Lisa; Hahm, Seung; Vlasuk, George P; Saiah, Eddine.
Afiliación
  • Kang SA; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA. Electronic address: skang@navitorpharma.com.
  • O'Neill DJ; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Machl AW; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Lumpkin CJ; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Galda SN; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Sengupta S; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Mahoney SJ; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Howell JJ; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Molz L; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Hahm S; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Vlasuk GP; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
  • Saiah E; Navitor Pharmaceuticals, Inc., 1030 Massachusetts Avenue, Suite 410, Cambridge, MA 02138, USA.
Cell Chem Biol ; 26(9): 1203-1213.e13, 2019 09 19.
Article en En | MEDLINE | ID: mdl-31231029
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Texto completo: 1 Colección: 01-internacional Asunto principal: Sirolimus / Proteínas Facilitadoras del Transporte de la Glucosa / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Chem Biol Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Sirolimus / Proteínas Facilitadoras del Transporte de la Glucosa / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Chem Biol Año: 2019 Tipo del documento: Article