Antitumor activity of saponin isolated from the sea cucumber, holothuria arenicola against ehrlich ascites carcinoma cells in swiss albino mice.
Nat Prod Res
; 35(11): 1928-1932, 2021 Jun.
Article
en En
| MEDLINE
| ID: mdl-31343268
ABSTRACT
The present investigation attempted study the potential use of the Holothuria arenicola saponin (HaS) against Ehrlich Ascites Carcinoma (EAC) tumor model in female Swiss albino mice. The HPLC studies of the extracted saponin showed the peak at retention time 5.19 min. was is matched with the standard saponin with total amount 34.87%. Significant improvements were detected in the tumor markers, complete blood count, antioxidant system, liver function and kidney function of HaS-treated mice. The present study demonstrated that HaS is a potent natural product that has promising antineoplastic efficacy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Ascitis
/
Saponinas
/
Carcinoma de Ehrlich
/
Holothuria
/
Antineoplásicos
Límite:
Animals
Idioma:
En
Revista:
Nat Prod Res
Año:
2021
Tipo del documento:
Article
País de afiliación:
Egipto