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Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.
Bian, Yansong; Teper, Yaroslav; Mathews Griner, Lesley A; Aiken, Taylor J; Shukla, Vivek; Guha, Rajarshi; Shinn, Paul; Xin, Hong-Wu; Pflicke, Holger; Powers, Astin S; Li, Dandan; Jiang, Jian-Kang; Patel, Paresma; Rogers, Steven A; Aubé, Jeffrey; Ferrer, Marc; Thomas, Craig J; Rudloff, Udo.
Afiliación
  • Bian Y; Rare Tumor Initiative, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Teper Y; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Mathews Griner LA; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Aiken TJ; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Shukla V; Department of Surgery, University of Wisconsin, Madison, Wisconsin.
  • Guha R; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Shinn P; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Xin HW; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Pflicke H; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Powers AS; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Li D; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Jiang JK; Rare Tumor Initiative, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Patel P; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Rogers SA; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Aubé J; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, Chapel Hill, North Carolina.
  • Ferrer M; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, Chapel Hill, North Carolina.
  • Thomas CJ; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Rudloff U; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland. rudloffu@mail.nih.gov craigt@mail.nih.gov.
Mol Cancer Ther ; 18(11): 2097-2110, 2019 11.
Article en En | MEDLINE | ID: mdl-31395684
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Pancreáticas / Células Madre Neoplásicas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Imidazoles Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Pancreáticas / Células Madre Neoplásicas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Imidazoles Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article