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Shunt Failure-The First 30 Days.
Lee, Ryan P; Ajmera, Sonia; Thomas, Fridtjof; Dave, Pooja; Lillard, Jock C; Wallace, David; Broussard, Austin; Motiwala, Mustafa; Norrdahl, Sebastian P; Venable, Garrett T; Khan, Nickalus R; Harrell, Camden; Jones, Tamekia L; Vaughn, Brandy N; Gooldy, Tim; Hersh, David S; Klimo, Paul.
Afiliación
  • Lee RP; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Ajmera S; College of Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Thomas F; Division of Biostatistics, Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Dave P; Rhodes College, Memphis, Tennessee.
  • Lillard JC; Department of Neurosurgery, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Wallace D; College of Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Broussard A; College of Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Motiwala M; College of Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Norrdahl SP; College of Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Venable GT; Department of Neurosurgery, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Khan NR; Department of Neurosurgery, The University of Tennessee Health Science Center, Memphis, Tennessee.
  • Harrell C; Department of Pediatrics, The University of Tennessee Health Science Center, Children's Foundation Research Institute, Memphis, Tennessee.
  • Jones TL; Department of Preventive Medicine, The University of Tennessee Health Science Center, Children's Foundation Research Institute, Memphis, Tennessee.
  • Vaughn BN; Department of Pediatrics, The University of Tennessee Health Science Center, Children's Foundation Research Institute, Memphis, Tennessee.
  • Gooldy T; Department of Preventive Medicine, The University of Tennessee Health Science Center, Children's Foundation Research Institute, Memphis, Tennessee.
  • Hersh DS; Le Bonheur Children's Hospital, Memphis, Tennessee.
  • Klimo P; Department of Neurosurgery, The University of Tennessee Health Science Center, Memphis, Tennessee.
Neurosurgery ; 87(1): 123-129, 2020 07 01.
Article en En | MEDLINE | ID: mdl-31557298
ABSTRACT

BACKGROUND:

Incontrovertible predictors of shunt malfunction remain elusive.

OBJECTIVE:

To determine predictors of shunt failure within 30 d of index surgery.

METHODS:

This was a single-center retrospective cohort study from January 2010 through November 2016. Using a ventricular shunt surgery research database, clinical and procedural variables were procured. An "index surgery" was defined as implantation of a new shunt or revision or augmentation of an existing shunt system. The primary outcome was shunt failure of any kind within the first 30 days of index surgery. Bivariate models were created, followed by a final multivariable logistic regression model using a backward-forward selection procedure.

RESULTS:

Our dataset contained 655 unique patients with a total of 1206 operations. The median age for the cohort at the time of first shunt surgery was 4.6 yr (range, 0-28; first and third quartile, .37 and 11.8, respectively). The 30-day failure rates were 12.4% when analyzing the first-index operation only (81/655), and 15.7% when analyzing all-index operations (189/1206). Small or slit ventricles at the time of index surgery and prior ventricular shunt operations were found to be significant covariates in both the "first-index" (P < .01 and P = .05, respectively) and "all-index" (P = .02 and P < .01, respectively) multivariable models. Intraventricular hemorrhage at the time of index surgery was an additional predictor in the all-index model (P = .01).

CONCLUSION:

This study demonstrates that only 3 variables are predictive of 30-day shunt failure when following established variable selection procedures, 2 of which are potentially under direct control of the surgeon.
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Texto completo: 1 Colección: 01-internacional Asunto principal: Ventrículos Cerebrales / Derivación Ventriculoperitoneal / Insuficiencia del Tratamiento / Hidrocefalia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Neurosurgery Año: 2020 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Asunto principal: Ventrículos Cerebrales / Derivación Ventriculoperitoneal / Insuficiencia del Tratamiento / Hidrocefalia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Neurosurgery Año: 2020 Tipo del documento: Article