Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5'-Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C<sub>35</sub> Bacteriohopanepolyols.

Sato, Shusuke; Kudo, Fumitaka; Rohmer, Michel; Eguchi, Tadashi

Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5'-Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C₃₅ Bacteriohopanepolyols.

Sato, Shusuke; Kudo, Fumitaka; Rohmer, Michel; Eguchi, Tadashi.

Afiliación

Sato S; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo, 152-8551, Japan.
Kudo F; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo, 152-8551, Japan.
Rohmer M; Institut Le Bel, Université de Strasbourg/CNRS, 4 rue Blaise Pascal, 67070, Strasbourg Cedex, France.
Eguchi T; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo, 152-8551, Japan.

Angew Chem Int Ed Engl ; 59(1): 237-241, 2020 01 02.

Article en En | MEDLINE | ID: mdl-31657500

Asunto(s)

Adenosina/análogos & derivados; Proteínas Bacterianas/metabolismo; S-Adenosilmetionina/química; Triterpenos/química; Adenosina/química; Catálisis; Humanos

Palabras clave

adenosylhopane; biosynthesis; hopanoid; radical SAM enzymes; terpenoids

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Texto completo: 1 Colección: 01-internacional Asunto principal: S-Adenosilmetionina / Proteínas Bacterianas / Triterpenos / Adenosina Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: Japón

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