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Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.
Rokita, Jo Lynne; Rathi, Komal S; Cardenas, Maria F; Upton, Kristen A; Jayaseelan, Joy; Cross, Katherine L; Pfeil, Jacob; Egolf, Laura E; Way, Gregory P; Farrel, Alvin; Kendsersky, Nathan M; Patel, Khushbu; Gaonkar, Krutika S; Modi, Apexa; Berko, Esther R; Lopez, Gonzalo; Vaksman, Zalman; Mayoh, Chelsea; Nance, Jonas; McCoy, Kristyn; Haber, Michelle; Evans, Kathryn; McCalmont, Hannah; Bendak, Katerina; Böhm, Julia W; Marshall, Glenn M; Tyrrell, Vanessa; Kalletla, Karthik; Braun, Frank K; Qi, Lin; Du, Yunchen; Zhang, Huiyuan; Lindsay, Holly B; Zhao, Sibo; Shu, Jack; Baxter, Patricia; Morton, Christopher; Kurmashev, Dias; Zheng, Siyuan; Chen, Yidong; Bowen, Jay; Bryan, Anthony C; Leraas, Kristen M; Coppens, Sara E; Doddapaneni, HarshaVardhan; Momin, Zeineen; Zhang, Wendong; Sacks, Gregory I; Hart, Lori S; Krytska, Kateryna.
Afiliación
  • Rokita JL; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Center for Data-Drive
  • Rathi KS; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Cardenas MF; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Upton KA; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA.
  • Jayaseelan J; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Cross KL; Guardian Forensic Sciences, Abington, PA 19001, USA.
  • Pfeil J; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
  • Egolf LE; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA; Cell and Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Way GP; Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Farrel A; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Kendsersky NM; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Patel K; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Gaonkar KS; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Modi A; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA; Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Berko ER; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA.
  • Lopez G; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Vaksman Z; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Mayoh C; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • Nance J; Cancer Center, Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX 79430, USA.
  • McCoy K; Cancer Center, Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX 79430, USA.
  • Haber M; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • Evans K; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • McCalmont H; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • Bendak K; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • Böhm JW; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia.
  • Marshall GM; Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia; Sydney Children's Hospital, Sydney, NSW, Australia.
  • Tyrrell V; Children's Cancer Institute, Kensington, NSW, Australia.
  • Kalletla K; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Braun FK; Texas Children's Cancer and Hematology Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Qi L; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Du Y; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Zhang H; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Lindsay HB; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Zhao S; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Shu J; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Baxter P; Preclinical Neurooncology Research Program, Texas Children's Cancer Research Center, Texas Children's Hospital, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Morton C; Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Kurmashev D; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX 78229, USA.
  • Zheng S; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX 78229, USA.
  • Chen Y; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX 78229, USA.
  • Bowen J; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
  • Bryan AC; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
  • Leraas KM; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
  • Coppens SE; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
  • Doddapaneni H; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Momin Z; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Zhang W; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sacks GI; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA.
  • Hart LS; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA.
  • Krytska K; Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA.
Cell Rep ; 29(6): 1675-1689.e9, 2019 11 05.
Article en En | MEDLINE | ID: mdl-31693904
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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteína p53 Supresora de Tumor / Neoplasias del Sistema Nervioso Central / Ensayos Antitumor por Modelo de Xenoinjerto / Neurofibromina 1 / Leucemia-Linfoma Linfoblástico de Células Precursoras Límite: Animals / Child / Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteína p53 Supresora de Tumor / Neoplasias del Sistema Nervioso Central / Ensayos Antitumor por Modelo de Xenoinjerto / Neurofibromina 1 / Leucemia-Linfoma Linfoblástico de Células Precursoras Límite: Animals / Child / Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article