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Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo.
Gammon, Seth T; Pisaneschi, Federica; Bandi, Madhavi L; Smith, Melinda G; Sun, Yuting; Rao, Yi; Muller, Florian; Wong, Franklin; De Groot, John; Ackroyd, Jeffrey; Mawlawi, Osama; Davies, Michael A; Gopal, Y N Vashisht; Di Francesco, M Emilia; Marszalek, Joseph R; Dewhirst, Mark; Piwnica-Worms, David.
Afiliación
  • Gammon ST; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Pisaneschi F; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Bandi ML; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Smith MG; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sun Y; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Rao Y; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Muller F; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wong F; Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • De Groot J; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX,77030, USA.
  • Ackroyd J; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mawlawi O; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Gopal YNV; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Di Francesco ME; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Marszalek JR; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Dewhirst M; Department of Radiation Oncology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Piwnica-Worms D; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Cells ; 8(12)2019 11 21.
Article en En | MEDLINE | ID: mdl-31766580

Texto completo: 1 Colección: 01-internacional Asunto principal: Oxadiazoles / Piperidinas / Complejo I de Transporte de Electrón / Hipoxia Tumoral Límite: Animals / Female / Humans Idioma: En Revista: Cells Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Asunto principal: Oxadiazoles / Piperidinas / Complejo I de Transporte de Electrón / Hipoxia Tumoral Límite: Animals / Female / Humans Idioma: En Revista: Cells Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos