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Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
Sherekar, Mukul; Han, Sae-Won; Ghirlando, Rodolfo; Messing, Simon; Drew, Matthew; Rabara, Dana; Waybright, Timothy; Juneja, Puneet; O'Neill, Hugh; Stanley, Christopher B; Bhowmik, Debsindhu; Ramanathan, Arvind; Subramaniam, Sriram; Nissley, Dwight V; Gillette, William; McCormick, Frank; Esposito, Dominic.
Afiliación
  • Sherekar M; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Han SW; Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94158.
  • Ghirlando R; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
  • Messing S; Laboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Drew M; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Rabara D; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Waybright T; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Juneja P; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • O'Neill H; Robert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, Georgia 30322.
  • Stanley CB; Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830.
  • Bhowmik D; Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830.
  • Ramanathan A; Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830.
  • Subramaniam S; Argonne National Laboratory, Lemont, Illinois 60439.
  • Nissley DV; Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Gillette W; Department of Biochemistry, Life Sciences Center, University of British Columbia, Vancouver, British Columbia V6T1Z3, Canada.
  • McCormick F; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
  • Esposito D; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702.
J Biol Chem ; 295(4): 1105-1119, 2020 01 24.
Article en En | MEDLINE | ID: mdl-31836666
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neurofibromina 1 / Multimerización de Proteína Límite: Humans Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neurofibromina 1 / Multimerización de Proteína Límite: Humans Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article