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GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment.
Halaby, Marie Jo; Hezaveh, Kebria; Lamorte, Sara; Ciudad, M Teresa; Kloetgen, Andreas; MacLeod, Bethany L; Guo, Mengdi; Chakravarthy, Ankur; Medina, Tiago Da Silva; Ugel, Stefano; Tsirigos, Aristotelis; Bronte, Vincenzo; Munn, David H; Pugh, Trevor J; De Carvalho, Daniel D; Butler, Marcus O; Ohashi, Pamela S; Brooks, David G; McGaha, Tracy L.
Afiliación
  • Halaby MJ; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Hezaveh K; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Lamorte S; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Ciudad MT; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Kloetgen A; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • MacLeod BL; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Guo M; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Chakravarthy A; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Medina TDS; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Ugel S; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Tsirigos A; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Bronte V; Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Munn DH; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Pugh TJ; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • De Carvalho DD; A.C. Camargo Cancer Center, Sao Paulo, Brazil.
  • Butler MO; Department of Medicine, Immunology Section, Verona University Hospital, Verona, Italy.
  • Ohashi PS; Department of Pathology, New York University School of Medicine, New York, NY, USA.
  • Brooks DG; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.
  • McGaha TL; Applied Bioinformatics Laboratories, New York University School of Medicine, New York, NY, USA.
Sci Immunol ; 4(42)2019 12 13.
Article en En | MEDLINE | ID: mdl-31836669

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Serina-Treonina Quinasas / Linfocitos T CD8-positivos / Microambiente Tumoral / Células Supresoras de Origen Mieloide / Macrófagos / Melanoma Límite: Animals / Humans Idioma: En Revista: Sci Immunol Año: 2019 Tipo del documento: Article País de afiliación: Canadá

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Serina-Treonina Quinasas / Linfocitos T CD8-positivos / Microambiente Tumoral / Células Supresoras de Origen Mieloide / Macrófagos / Melanoma Límite: Animals / Humans Idioma: En Revista: Sci Immunol Año: 2019 Tipo del documento: Article País de afiliación: Canadá