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Treatment with rapamycin can restore regulatory T-cell function in IPEX patients.
Passerini, Laura; Barzaghi, Federica; Curto, Rosalia; Sartirana, Claudia; Barera, Graziano; Tucci, Francesca; Albarello, Luca; Mariani, Alberto; Testoni, Pier Alberto; Bazzigaluppi, Elena; Bosi, Emanuele; Lampasona, Vito; Neth, Olaf; Zama, Daniele; Hoenig, Manfred; Schulz, Ansgar; Seidel, Markus G; Rabbone, Ivana; Olek, Sven; Roncarolo, Maria G; Cicalese, Maria P; Aiuti, Alessandro; Bacchetta, Rosa.
Afiliación
  • Passerini L; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Barzaghi F; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Paediatric Immunohematology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Curto R; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Sartirana C; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Barera G; Department of Paediatrics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Tucci F; Department of Paediatric Immunohematology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Albarello L; Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Mariani A; Gastroenterology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Testoni PA; Gastroenterology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bazzigaluppi E; Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bosi E; Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita Salute San Raffaele University, Milan, Italy.
  • Lampasona V; Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Neth O; Department of Paediatric Infectious Diseases, Rheumatology and Immunodeficiency, Instituto de Biomedicina de Sevilla/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, Seville, Spain.
  • Zama D; Department of Pediatrics, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Hoenig M; Clinic of Pediatrics and Adolescent Medicine, Ulm University, Ulm, Germany.
  • Schulz A; Clinic of Pediatrics and Adolescent Medicine, Ulm University, Ulm, Germany.
  • Seidel MG; Division of Pediatric Hematology/Oncology, Department of Pediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria.
  • Rabbone I; Department of Pediatrics, University of Turin, Turin, Italy.
  • Olek S; Epiontis GmbH, Berlin, Germany.
  • Roncarolo MG; Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, Calif.
  • Cicalese MP; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Paediatric Immunohematology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Aiuti A; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Paediatric Immunohematology, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita Salute San Raffaele University, Milan, Italy.
  • Bacchetta R; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, Calif. Electronic address: rosab@stanford.e
J Allergy Clin Immunol ; 145(4): 1262-1271.e13, 2020 04.
Article en En | MEDLINE | ID: mdl-31874182
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Texto completo: 1 Colección: 01-internacional Asunto principal: Linfocitos T Reguladores / Sirolimus / Enfermedades Genéticas Ligadas al Cromosoma X / Diabetes Mellitus Tipo 1 / Diarrea / Factores de Transcripción Forkhead / Enfermedades del Sistema Inmune / Inmunosupresores / Mutación Límite: Child / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Linfocitos T Reguladores / Sirolimus / Enfermedades Genéticas Ligadas al Cromosoma X / Diabetes Mellitus Tipo 1 / Diarrea / Factores de Transcripción Forkhead / Enfermedades del Sistema Inmune / Inmunosupresores / Mutación Límite: Child / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2020 Tipo del documento: Article País de afiliación: Italia