The M Protein of Streptococcus pyogenes Strain AP53 Retains Cell Surface Functional Plasminogen Binding after Inactivation of the Sortase A Gene.

Russo, Brady T; Ayinuola, Yetunde A; Singh, Damini; Carothers, Katelyn; Fischetti, Vincent A; Flores-Mireles, Ana L; Lee, Shaun W; Ploplis, Victoria A; Liang, Zhong; Castellino, Francis J

Russo, Brady T; Ayinuola, Yetunde A; Singh, Damini; Carothers, Katelyn; Fischetti, Vincent A; Flores-Mireles, Ana L; Lee, Shaun W; Ploplis, Victoria A; Liang, Zhong; Castellino, Francis J.

Afiliación

Russo BT; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
Ayinuola YA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
Singh D; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
Carothers K; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
Fischetti VA; Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Flores-Mireles AL; Laboratory of Bacterial Pathogenesis and Immunology, Rockefeller University, New York, New York, USA.
Lee SW; Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Ploplis VA; Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Liang Z; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
Castellino FJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.

J Bacteriol ; 202(10)2020 04 27.

Article en En | MEDLINE | ID: mdl-32123038

Asunto(s)

Aminoaciltransferasas/metabolismo; Proteínas Bacterianas/metabolismo; Cisteína Endopeptidasas/metabolismo; Proteínas de la Membrana/metabolismo; Plasminógeno/metabolismo; Infecciones Estreptocócicas/metabolismo; Streptococcus pyogenes/metabolismo; Aminoaciltransferasas/genética; Proteínas Bacterianas/genética; Cisteína Endopeptidasas/genética; Humanos; Proteínas de la Membrana/genética; Unión Proteica; Infecciones Estreptocócicas/microbiología; Streptococcus pyogenes/enzimología; Streptococcus pyogenes/genética

Palabras clave

bacterial M protein; bacterial mutants; bacterial plasminogen receptors; bacterium-host interactions; cell surface proteins; plasminogen binding; sortase A

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Texto completo: 1 Colección: 01-internacional Asunto principal: Plasminógeno / Infecciones Estreptocócicas / Streptococcus pyogenes / Proteínas Bacterianas / Cisteína Endopeptidasas / Aminoaciltransferasas / Proteínas de la Membrana Límite: Humans Idioma: En Revista: J Bacteriol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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