Pesticides, cosmetics, drugs: identical and opposite influences of various molecular features as measures of endpoints similarity and dissimilarity.

Toropov, Andrey A; Toropova, Alla P; Marzo, Marco; Carnesecchi, Edoardo; Selvestrel, Gianluca; Benfenati, Emilio

Toropov, Andrey A; Toropova, Alla P; Marzo, Marco; Carnesecchi, Edoardo; Selvestrel, Gianluca; Benfenati, Emilio.

Afiliación

Toropov AA; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy.
Toropova AP; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy. alla.toropova@marionegri.it.
Marzo M; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy.
Carnesecchi E; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy.
Selvestrel G; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80177, 3508 TD, Utrecht, The Netherlands.
Benfenati E; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy.

Mol Divers ; 25(2): 1137-1144, 2021 May.

Article en En | MEDLINE | ID: mdl-32323128

Asunto(s)

Modelos Moleculares; Aminas/química; Aminas/toxicidad; Animales; Ansiolíticos/química; Ansiolíticos/toxicidad; Antidepresivos/química; Antidepresivos/toxicidad; Antipsicóticos/química; Antipsicóticos/toxicidad; Cosméticos/química; Cosméticos/toxicidad; Inhibidores de la Proteasa del VIH/química; Inhibidores de la Proteasa del VIH/farmacología; Haptenos/química; Haptenos/toxicidad; Humanos; Dosificación Letal Mediana; Ensayo del Nódulo Linfático Local; Mutágenos/química; Mutágenos/toxicidad; Oncorhynchus mykiss; Plaguicidas/química; Plaguicidas/toxicidad; Fenotiazinas/química; Fenotiazinas/toxicidad; Relación Estructura-Actividad Cuantitativa; Salmonella typhimurium/efectos de los fármacos; Salmonella typhimurium/genética

Palabras clave

Biochemical endpoints; Index of ideality of correlation; Monte Carlo method; QSAR; Similarity/dissimilarity of endpoints

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Texto completo: 1 Colección: 01-internacional Asunto principal: Modelos Moleculares Límite: Animals / Humans Idioma: En Revista: Mol Divers Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Italia

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