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New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation.
Bortolami, Martina; Pandolfi, Fabiana; De Vita, Daniela; Carafa, Camilla; Messore, Antonella; Di Santo, Roberto; Feroci, Marta; Costi, Roberta; Chiarotto, Isabella; Bagetta, Donatella; Alcaro, Stefano; Colone, Marisa; Stringaro, Annarita; Scipione, Luigi.
Afiliación
  • Bortolami M; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
  • Pandolfi F; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, I-00161, Rome, Italy.
  • De Vita D; Department of Environmental Biology, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
  • Carafa C; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
  • Messore A; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
  • Di Santo R; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy; Istituto Pasteur, Fondazione Cenci Bolognetti, Department of Chemistry and Technology of Drug, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
  • Feroci M; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, I-00161, Rome, Italy.
  • Costi R; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy; Istituto Pasteur, Fondazione Cenci Bolognetti, Department of Chemistry and Technology of Drug, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
  • Chiarotto I; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, I-00161, Rome, Italy.
  • Bagetta D; Net4Science s.r.l., Campus universitario "S. Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Alcaro S; Net4Science s.r.l., Campus universitario "S. Venuta", Viale Europa, 88100, Catanzaro, Italy; Dipartimento di Scienze della Salute, Università"Magna Græcia" di Catanzaro, Viale Europa, 88100, Catanzaro, Italy. Electronic address: alcaro@unicz.it.
  • Colone M; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Viale Regina Elena, 00161, Rome, Italy.
  • Stringaro A; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Viale Regina Elena, 00161, Rome, Italy.
  • Scipione L; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy. Electronic address: luigi.scipione@uniroma1.it.
Eur J Med Chem ; 198: 112350, 2020 Jul 15.
Article en En | MEDLINE | ID: mdl-32380385
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Texto completo: 1 Colección: 01-internacional Asunto principal: Acetilcolinesterasa / Quelantes del Hierro / Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Deferiprona Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Acetilcolinesterasa / Quelantes del Hierro / Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Deferiprona Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: Italia