Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton.

Rogers, Michael J; Mönkkönen, Jukka; Munoz, Marcia A

Rogers, Michael J; Mönkkönen, Jukka; Munoz, Marcia A.

Afiliación

Rogers MJ; Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, UNSW Sydney, Australia. Electronic address: m.rogers@garvan.org.au.
Mönkkönen J; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Finland. Electronic address: jukka.monkkonen@uef.fi.
Munoz MA; Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, UNSW Sydney, Australia. Electronic address: m.munoz@garvan.org.au.

Bone ; 139: 115493, 2020 10.

Article en En | MEDLINE | ID: mdl-32569873

Asunto(s)

Resorción Ósea; Difosfonatos; Resorción Ósea/tratamiento farmacológico; Huesos; Difosfonatos/farmacología; Humanos; Osteoclastos; Prenilación de Proteína

Palabras clave

Bisphosphonate; Bone resorption; Clodronate; FPP; Farnesyl; GGPP; Geranylgeranyl; IPP; Isoprenoid; Macrophage; Mevalonate; Osteoclast; Prenylation; Small GTPase; Zoledronate; Î³,Î´-T cell

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Texto completo: 1 Colección: 01-internacional Asunto principal: Resorción Ósea / Difosfonatos Límite: Humans Idioma: En Revista: Bone Asunto de la revista: METABOLISMO / ORTOPEDIA Año: 2020 Tipo del documento: Article

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