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7-Deaza-7-fluoro-2'-C-methyladenosine inhibits Zika virus infection and viral-induced neuroinflammation.
Del Sarto, Juliana Lemos; Rocha, Rebeca de Paiva Froes; Bassit, Leda; Olmo, Isabella Guimarães; Valiate, Bruno; Queiroz-Junior, Celso M; Pedrosa, Carolina da Silva Gouveia; Ribeiro, Fabíola Mara; Guimarães, Marilia Zaluar; Rehen, Stevens; Amblard, Franck; Zhou, Longhu; Cox, Bryan D; Gavegnano, Christina; Costa, Vivian Vasconcelos; Schinazi, Raymond F; Teixeira, Mauro Martins.
Afiliación
  • Del Sarto JL; Department of Biochemistry and Immunology, And(2)Research Center for Drug Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Rocha RPF; Department of Biochemistry and Immunology, And(2)Research Center for Drug Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Bassit L; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Olmo IG; Neurobiochemistry Laboratory, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Minas Gerais, Brazil.
  • Valiate B; Department of Biochemistry and Immunology, And(2)Research Center for Drug Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Queiroz-Junior CM; Cardiac Biology Laboratory, Department of Morphology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
  • Pedrosa CDSG; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
  • Ribeiro FM; Neurobiochemistry Laboratory, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Minas Gerais, Brazil.
  • Guimarães MZ; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Rehen S; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Amblard F; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Zhou L; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Cox BD; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Gavegnano C; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Costa VV; Department of Biochemistry and Immunology, And(2)Research Center for Drug Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Research Group in Arboviral Diseases. Department of Morphology, Institute of Biological Sciences (ICB), U
  • Schinazi RF; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA. Electronic address: rschina@emory.edu.
  • Teixeira MM; Department of Biochemistry and Immunology, And(2)Research Center for Drug Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address: mmtex@icb.ufmg.br.
Antiviral Res ; 180: 104855, 2020 08.
Article en En | MEDLINE | ID: mdl-32574688
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Texto completo: 1 Colección: 01-internacional Asunto principal: Antivirales / Adenosina / Infección por el Virus Zika / Inflamación / Enfermedades del Sistema Nervioso Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2020 Tipo del documento: Article País de afiliación: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Antivirales / Adenosina / Infección por el Virus Zika / Inflamación / Enfermedades del Sistema Nervioso Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2020 Tipo del documento: Article País de afiliación: Brasil