[A case of meningeal melanomatosis diagnosed by immunostaining of cerebrospinal fluid].
Rinsho Shinkeigaku
; 60(8): 565-568, 2020 Aug 07.
Article
en Ja
| MEDLINE
| ID: mdl-32641630
ABSTRACT
A 49-year-old woman was admitted to our hospital with suspected hypertensive encephalopathy. On the basis of MRI showing leptomeningeal enhancement and Class V cytology of the CSF, she was diagnosed as having leptomeningeal carcinomatosis. Although no primary site was detected, a few melanin granules were observed at the third CSF examination. The atypical cells in the CSF demonstrated immunoreactivity for HMB-45 and S-100, which are specific markers of malignant melanoma. There have been few reports of meningeal melanomatosis in Japan. This case illustrates that immunostaining is diagnostically useful in patients with leptomeningeal carcinomatosis from neoplasms with unknown primary sites.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Coloración y Etiquetado
/
Biomarcadores de Tumor
/
Líquido Cefalorraquídeo
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Citodiagnóstico
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Carcinomatosis Meníngea
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Melanoma
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Neoplasias Meníngeas
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
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Female
/
Humans
Idioma:
Ja
Revista:
Rinsho Shinkeigaku
Año:
2020
Tipo del documento:
Article