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Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Li, Baicun; Yao, Jie; Guo, Kaiqiang; He, Fengming; Chen, Kun; Lin, Zongxin; Liu, Shunzhi; Huang, Jiangang; Wu, Qiaoqiong; Fang, Meijuan; Zeng, Jinzhang; Wu, Zhen.
Afiliación
  • Li B; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China; State Key Laboratory of Medical Molecular Biology, Department of Physiology, Institute of Basic Medica
  • Yao J; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Guo K; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • He F; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Chen K; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Lin Z; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Liu S; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Huang J; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Wu Q; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China.
  • Fang M; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China. Electronic address: fangmj@xmu.edu.cn.
  • Zeng J; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China. Electronic address: jzzeng@xmu.edu.cn.
  • Wu Z; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China. Electronic address: wuzhen@xmu.edu.cn.
Eur J Med Chem ; 204: 112608, 2020 Oct 15.
Article en En | MEDLINE | ID: mdl-32717483

Texto completo: 1 Colección: 01-internacional Asunto principal: Diseño de Fármacos / Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Hidrazinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Asunto principal: Diseño de Fármacos / Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Hidrazinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article