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Hyperpolarized [1-13C]pyruvate-to-[1-13C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane.
Rao, Yi; Gammon, Seth; Zacharias, Niki M; Liu, Tracy; Salzillo, Travis; Xi, Yuanxin; Wang, Jing; Bhattacharya, Pratip; Piwnica-Worms, David.
Afiliación
  • Rao Y; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Gammon S; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Zacharias NM; Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Liu T; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Salzillo T; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Xi Y; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Wang J; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Bhattacharya P; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Piwnica-Worms D; Department of Cancer System Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030; dpiwnica-worms@mdanderson.org.
Proc Natl Acad Sci U S A ; 117(36): 22378-22389, 2020 09 08.
Article en En | MEDLINE | ID: mdl-32839325
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Texto completo: 1 Colección: 01-internacional Asunto principal: Isótopos de Carbono / Membrana Celular / Ácido Láctico / Ácido Pirúvico / Transportadores de Ácidos Monocarboxílicos / Simportadores Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Isótopos de Carbono / Membrana Celular / Ácido Láctico / Ácido Pirúvico / Transportadores de Ácidos Monocarboxílicos / Simportadores Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article