TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-&#954;B pro-oncogenic signaling pathway.

Chen, Huiyu; Ye, Yuhan; Yang, Yan; Zhong, Mengya; Gu, Lei; Han, Zhaopu; Qiu, Jinhua; Liu, Zhongchen; Qiu, Xingfeng; Zhuang, Guohong

TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway.

Chen, Huiyu; Ye, Yuhan; Yang, Yan; Zhong, Mengya; Gu, Lei; Han, Zhaopu; Qiu, Jinhua; Liu, Zhongchen; Qiu, Xingfeng; Zhuang, Guohong.

Afiliación

Chen H; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Ye Y; Department of Pathology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian, China.
Yang Y; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Zhong M; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Gu L; Department of General Surgery, Shanghai 10th People's Hospital Affiliated to Tongji University, Shanghai, China.
Han Z; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Qiu J; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Liu Z; Department of General Surgery, Shanghai 10th People's Hospital Affiliated to Tongji University, Shanghai, China. 13860184888@163.com.
Qiu X; Department of Gastrointestinal Surgery, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian, China. Dr.qxf@xmu.edu.cn.
Zhuang G; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China. zhgh@xmu.edu.cn.

Signal Transduct Target Ther ; 5(1): 163, 2020 08 25.

Article en En | MEDLINE | ID: mdl-32843639

Asunto(s)

Neoplasias Colorrectales/genética; Péptidos y Proteínas de Señalización Intracelular/genética; MAP Quinasa Quinasa 3/genética; Metaloproteinasa 9 de la Matriz/genética; Proliferación Celular/genética; Neoplasias Colorrectales/patología; Células HCT116; Humanos; Metaloproteinasa 1 de la Matriz/genética; FN-kappa B/genética; Invasividad Neoplásica/genética; Invasividad Neoplásica/patología; Metástasis de la Neoplasia; Transducción de Señal/genética; Proteínas Quinasas p38 Activadas por Mitógenos/genética

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Colorrectales / Metaloproteinasa 9 de la Matriz / MAP Quinasa Quinasa 3 / Péptidos y Proteínas de Señalización Intracelular Límite: Humans Idioma: En Revista: Signal Transduct Target Ther Año: 2020 Tipo del documento: Article País de afiliación: China

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