Non-invasive Assessment of Vaccine-Induced HPV Antibodies via First-Void Urine.
Front Immunol
; 11: 1657, 2020.
Article
en En
| MEDLINE
| ID: mdl-32849573
ABSTRACT
The potential of first-void (FV) urine as a non-invasive method to monitor human papillomavirus (HPV) vaccination has been reported, mainly focusing on urine as a sample to assess HPV DNA. Besides HPV DNA, vaccine-induced HPV antibodies originating from cervicovaginal secretions were recently shown to be detectable in FV urine as well. This presents a novel opportunity for non-invasive sampling to monitor HPV antibody status in women participating in large epidemiological studies and HPV vaccine trials. The simultaneous assessment of both HPV infection and immunogenicity on a non-invasive, readily obtained sample is particularly attractive.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Infecciones por Papillomavirus
/
Alphapapillomavirus
/
Vacunas contra Papillomavirus
/
Inmunogenicidad Vacunal
/
Anticuerpos Antivirales
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Front Immunol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Bélgica