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SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors.
Xia, Zong-Jun; Ji, Yin-Chun; Sun, De-Qiao; Peng, Xia; Gao, Ying-Lei; Fang, Yan-Fen; Zhao, Xing-Dong; Wang, Wei-Bo; Ding, Jian; Geng, Mei-Yu; Ai, Jing.
Afiliación
  • Xia ZJ; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Ji YC; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Sun DQ; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Peng X; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Gao YL; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Fang YF; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhao XD; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Wang WB; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Ding J; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Geng MY; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Ai J; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Acta Pharmacol Sin ; 42(6): 998-1004, 2021 Jun.
Article en En | MEDLINE | ID: mdl-32918045
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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China