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Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor.
Ribeiro, Jean F R; Cianni, Lorenzo; Li, Chan; Warwick, Thomas G; de Vita, Daniela; Rosini, Fabiana; Dos Reis Rocho, Fernanda; Martins, Felipe C P; Kenny, Peter W; Lameira, Jeronimo; Leitão, Andrei; Emsley, Jonas; Montanari, Carlos A.
Afiliación
  • Ribeiro JFR; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Cianni L; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Li C; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.
  • Warwick TG; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.
  • de Vita D; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Rosini F; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Dos Reis Rocho F; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Martins FCP; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Kenny PW; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Lameira J; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil; Laboratory of Design and Development of Pharmaceuticals, Federal University of Pará, Belém, Brazil.
  • Leitão A; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil.
  • Emsley J; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK. Electronic address: jonas.emsley@nottingham.ac.uk.
  • Montanari CA; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil. Electronic address: Carlos.Montanari@usp.br.
Bioorg Med Chem ; 28(22): 115743, 2020 11 15.
Article en En | MEDLINE | ID: mdl-33038787
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Texto completo: 1 Colección: 01-internacional Asunto principal: Compuestos Aza / Tripanocidas / Leishmania mexicana / Catepsina B / Inhibidores de Cisteína Proteinasa País/Región como asunto: Mexico Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Compuestos Aza / Tripanocidas / Leishmania mexicana / Catepsina B / Inhibidores de Cisteína Proteinasa País/Región como asunto: Mexico Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Brasil