Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain.

Kanda, Hirosato; Kobayashi, Kimiko; Yamanaka, Hiroki; Okubo, Masamichi; Dai, Yi; Noguchi, Koichi

Kanda, Hirosato; Kobayashi, Kimiko; Yamanaka, Hiroki; Okubo, Masamichi; Dai, Yi; Noguchi, Koichi.

Afiliación

Kanda H; Department of Pharmacology, Hyogo University of Health Sciences, Kobe, Hyogo 650-8530, Japan; Traditional Medicine Research Center, Chinese Medicine Confucius Institute at Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan; Department of Anatomy and Neuroscience, Hyogo College of Medicine
Kobayashi K; Department of Anatomy and Neuroscience, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.
Yamanaka H; Department of Anatomy and Neuroscience, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.
Okubo M; Department of Anatomy and Neuroscience, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.
Dai Y; Department of Pharmacology, Hyogo University of Health Sciences, Kobe, Hyogo 650-8530, Japan; Traditional Medicine Research Center, Chinese Medicine Confucius Institute at Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan; Department of Anatomy and Neuroscience, Hyogo College of Medicine
Noguchi K; Department of Anatomy and Neuroscience, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan. Electronic address: noguchi@hyo-med.ac.jp.

Brain Res ; 1750: 147153, 2021 01 01.

Article en En | MEDLINE | ID: mdl-33049240

Asunto(s)

Neuralgia/fisiopatología; Prostaglandina-E Sintasas/metabolismo; Receptores de Prostaglandina E/metabolismo; Animales; Sistema Nervioso Central/metabolismo; Ciclooxigenasa 2/metabolismo; Modelos Animales de Enfermedad; Células Endoteliales/metabolismo; Expresión Génica/genética; Oxidorreductasas Intramoleculares/metabolismo; Masculino; Umbral del Dolor/efectos de los fármacos; Prostaglandina-E Sintasas/fisiología; Ratas; Ratas Sprague-Dawley; Receptores de Prostaglandina E/fisiología; Subtipo EP4 de Receptores de Prostaglandina E/metabolismo; Médula Espinal/fisiología

Palabras clave

Endothelial cell; In situ hybridization; Neuropathic pain; Prostaglandin E2; Spinal cord; Tumor necrosis factor-α

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Texto completo: 1 Colección: 01-internacional Asunto principal: Receptores de Prostaglandina E / Prostaglandina-E Sintasas / Neuralgia Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Brain Res Año: 2021 Tipo del documento: Article

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