Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity.

Chatterjee, Anupriya; Eshwaran, Rachana; Poschet, Gernot; Lomada, Santosh; Halawa, Mahmoud; Wilhelm, Kerstin; Schmidt, Martina; Hammes, Hans-Peter; Wieland, Thomas; Feng, Yuxi

Chatterjee, Anupriya; Eshwaran, Rachana; Poschet, Gernot; Lomada, Santosh; Halawa, Mahmoud; Wilhelm, Kerstin; Schmidt, Martina; Hammes, Hans-Peter; Wieland, Thomas; Feng, Yuxi.

Afiliación

Chatterjee A; Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Eshwaran R; Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Poschet G; Centre for Organismal Studies (COS), 69120 Heidelberg, Germany.
Lomada S; Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Halawa M; Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Wilhelm K; Angiogenesis & Metabolism Laboratory, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
Schmidt M; Department of Molecular Pharmacology, University of Groningen, 9713 AV Groningen, The Netherlands.
Hammes HP; Groningen Research Institute for Asthma and COPD, GRIAC, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Wieland T; 5th Medical Clinic, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Feng Y; Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Cells ; 9(10)2020 10 19.

Article en En | MEDLINE | ID: mdl-33086728

Asunto(s)

Vías Biosintéticas; Células Endoteliales/metabolismo; Células Endoteliales/patología; Glucosa/metabolismo; Hexosaminas/biosíntesis; Nucleósido Difosfato Quinasas NM23/metabolismo; beta-N-Acetilhexosaminidasas/metabolismo; Angiopoyetina 2/metabolismo; Animales; Glicosilación; Células HEK293; Histidina/metabolismo; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Células Endoteliales de la Vena Umbilical Humana/patología; Humanos; Recién Nacido; Ratones; Modelos Biológicos; Nucleótidos/metabolismo

Palabras clave

Ang-2; O-GlcNAcylation; OGA; UDP-GlcNAc; nucleoside diphosphate kinase B

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Beta-N-Acetilhexosaminidasas / Células Endoteliales / Vías Biosintéticas / Nucleósido Difosfato Quinasas NM23 / Glucosa / Hexosaminas Límite: Animals / Humans / Newborn Idioma: En Revista: Cells Año: 2020 Tipo del documento: Article País de afiliación: Alemania

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google