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Gene duplication, rather than epigenetic changes, drives FGF4 overexpression in KIT/PDGFRA/SDH/RAS-P WT GIST.
Urbini, Milena; Astolfi, Annalisa; Indio, Valentina; Nannini, Margherita; Schipani, Angela; Bacalini, Maria Giulia; Angelini, Sabrina; Ravegnini, Gloria; Calice, Giovanni; Del Gaudio, Massimo; Secchiero, Paola; Ulivi, Paola; Gruppioni, Elisa; Pantaleo, Maria Abbondanza.
Afiliación
  • Urbini M; Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS, Meldola, Italy.
  • Astolfi A; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy. annalisa.astolfi@unife.it.
  • Indio V; "Giorgio Prodi" Cancer Research Center (CIRC), University of Bologna, Bologna, Italy.
  • Nannini M; Division of Oncology, Azienda Ospedaliero Universitaria di Bologna, Via Albertoni 15, Bologna, Italy.
  • Schipani A; "Giorgio Prodi" Cancer Research Center (CIRC), University of Bologna, Bologna, Italy.
  • Bacalini MG; Department of Experimental, Diagnostic and Specialized Medicine, University of Bologna, Bologna, Italy.
  • Angelini S; IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139, Bologna, Italy.
  • Ravegnini G; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Calice G; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Del Gaudio M; Laboratory of Preclinical and Translational Research, IRCCS-Referral Cancer Center of Basilicata (CROB), 85028, Rionero in Vulture, PZ, Italy.
  • Secchiero P; Department of Organ Insufficiencies and Transplantation, General Surgery and Transplantation, S. Orsola-Malpighi University Hospital, 40138, Bologna, Italy.
  • Ulivi P; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
  • Gruppioni E; Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS, Meldola, Italy.
  • Pantaleo MA; Laboratory of Oncologic Molecular Pathology, S. Orsola-Malpighi Hospital, Bologna, Italy.
Sci Rep ; 10(1): 19829, 2020 11 16.
Article en En | MEDLINE | ID: mdl-33199729
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Texto completo: 1 Colección: 01-internacional Asunto principal: Regulación hacia Arriba / Duplicación de Gen / Tumores del Estroma Gastrointestinal / Factor 4 de Crecimiento de Fibroblastos / Neoplasias Gastrointestinales Tipo de estudio: Prognostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Regulación hacia Arriba / Duplicación de Gen / Tumores del Estroma Gastrointestinal / Factor 4 de Crecimiento de Fibroblastos / Neoplasias Gastrointestinales Tipo de estudio: Prognostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Italia