Intralacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren's Syndrome.

Ju, Yaping; Edman, Maria C; Guo, Hao; Janga, Srikanth Reddy; Peddi, Santosh; Louie, Stan G; Junge, Jason A; MacKay, J Andrew; Hamm-Alvarez, Sarah F

Ju, Yaping; Edman, Maria C; Guo, Hao; Janga, Srikanth Reddy; Peddi, Santosh; Louie, Stan G; Junge, Jason A; MacKay, J Andrew; Hamm-Alvarez, Sarah F.

Afiliación

Ju Y; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90033, United States.
Edman MC; Department of Ophthalmology, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Guo H; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90033, United States.
Janga SR; Department of Ophthalmology, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Peddi S; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90033, United States.
Louie SG; Department of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California 90033, United States.
Junge JA; Department of Biological Sciences, Translational Imaging Center, Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, California 90089, United States.
MacKay JA; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90033, United States.
Hamm-Alvarez SF; Department of Ophthalmology, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.

Biomacromolecules ; 22(3): 1102-1114, 2021 03 08.

Article en En | MEDLINE | ID: mdl-33356170

Asunto(s)

Dacriocistitis; Aparato Lagrimal; Síndrome de Sjögren; Animales; Modelos Animales de Enfermedad; Masculino; Ratones; Ratones Endogámicos NOD; Sirolimus; Lágrimas

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Síndrome de Sjögren / Dacriocistitis / Aparato Lagrimal Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biomacromolecules Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google