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A RAC-GEF network critical for early intestinal tumourigenesis.
Pickering, K A; Gilroy, K; Cassidy, J W; Fey, S K; Najumudeen, A K; Zeiger, L B; Vincent, D F; Gay, D M; Johansson, J; Fordham, R P; Miller, B; Clark, W; Hedley, A; Unal, E B; Kiel, C; McGhee, E; Machesky, L M; Nixon, C; Johnsson, A E; Bain, M; Strathdee, D; van Hoof, S R; Medema, J P; Anderson, K I; Brachmann, S M; Stucke, V M; Malliri, A; Drysdale, M; Turner, M; Serrano, L; Myant, K; Campbell, A D; Sansom, O J.
Afiliación
  • Pickering KA; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Gilroy K; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Cassidy JW; CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 ORE, UK.
  • Fey SK; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Najumudeen AK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.
  • Zeiger LB; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Vincent DF; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Gay DM; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.
  • Johansson J; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Fordham RP; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Miller B; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Clark W; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Hedley A; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Unal EB; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Kiel C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • McGhee E; EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRC), Barcelona, Spain.
  • Machesky LM; Universitat Pompeu Fabra (UPF), 08003, Barcelona, Spain.
  • Nixon C; Institute for Theoretical Biology, Humboldt Universität zu Berlin, Berlin, Germany.
  • Johnsson AE; EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRC), Barcelona, Spain.
  • Bain M; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Strathdee D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • van Hoof SR; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.
  • Medema JP; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Anderson KI; The Babraham Institute, Babraham Hall, Babraham, Cambridge, CB22 3AT, UK.
  • Brachmann SM; IBAHCM and School of Veterinary Medicine, 464 Bearsden Road, Bearsden, Glasgow, G61 1QH, UK.
  • Stucke VM; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
  • Malliri A; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM) and Cancer Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.
  • Drysdale M; Oncode Institute, Academic Medical Center, Amsterdam, The Netherlands.
  • Turner M; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM) and Cancer Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.
  • Serrano L; Oncode Institute, Academic Medical Center, Amsterdam, The Netherlands.
  • Myant K; The Francis Crick Institute, Mill Hill Laboratory, London, NW7 1AA, UK.
  • Campbell AD; Novartis Institutes for BioMedical Research, Klybeckstrasse, 141, 4002, Basel, Switzerland.
  • Sansom OJ; Novartis Institutes for BioMedical Research, Klybeckstrasse, 141, 4002, Basel, Switzerland.
Nat Commun ; 12(1): 56, 2021 01 04.
Article en En | MEDLINE | ID: mdl-33397922

Texto completo: 1 Colección: 01-internacional Asunto principal: Transducción de Señal / Proteína de Unión al GTP rac1 / Factores de Intercambio de Guanina Nucleótido / Carcinogénesis / Intestinos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Asunto principal: Transducción de Señal / Proteína de Unión al GTP rac1 / Factores de Intercambio de Guanina Nucleótido / Carcinogénesis / Intestinos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido