Synthesis and characterization of hydrogels based on carboxymethyl chitosan and poly(vinylpyrrolidone) blends prepared by electron beam irradiation having anticancer efficacy, and applications as drug carrier for controlled release of drug.

Raza, Muhammad Asim; Lim, Youn-Mook; Lee, Se-Won; Seralathan, Kamala-Kannan; Park, Sang Hyun

Raza, Muhammad Asim; Lim, Youn-Mook; Lee, Se-Won; Seralathan, Kamala-Kannan; Park, Sang Hyun.

Afiliación

Raza MA; Advanced Radiation Technology Institute (ARTI), Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk, 56212, Republic of Korea; Radiation Science and Technology, University of Science and Technology, Daejeon, 34113, Republic of Korea.
Lim YM; Advanced Radiation Technology Institute (ARTI), Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk, 56212, Republic of Korea.
Lee SW; Division of Biotechnology, Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan, Jeonbuk, 54596, Republic of Korea.
Seralathan KK; Division of Biotechnology, Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan, Jeonbuk, 54596, Republic of Korea.
Park SH; Advanced Radiation Technology Institute (ARTI), Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk, 56212, Republic of Korea; Radiation Science and Technology, University of Science and Technology, Daejeon, 34113, Republic of Korea. Electronic address: parksh@kaeri.re.kr.

Carbohydr Polym ; 258: 117718, 2021 Apr 15.

Article en En | MEDLINE | ID: mdl-33593580

Asunto(s)

Antineoplásicos/administración & dosificación; Quitosano/análogos & derivados; Portadores de Fármacos; Sistemas de Liberación de Medicamentos; Hidrogeles/química; Kanamicina/administración & dosificación; Povidona/química; Animales; Línea Celular Tumoral; Supervivencia Celular; Quitosano/química; Reactivos de Enlaces Cruzados/química; Preparaciones de Acción Retardada; Difusión; Liberación de Fármacos; Electrones; Concentración de Iones de Hidrógeno; Técnicas In Vitro; Kanamicina/farmacología; Ratones; Microscopía Electrónica de Rastreo; Porosidad; Células RAW 264.7; Espectroscopía Infrarroja por Transformada de Fourier

Palabras clave

Carboxymethyl chitosan; Cell viability; Electron beam; Hydrogel; Poly(vinylpyrrolidone); Swelling

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Texto completo: 1 Colección: 01-internacional Asunto principal: Portadores de Fármacos / Kanamicina / Povidona / Sistemas de Liberación de Medicamentos / Hidrogeles / Quitosano / Antineoplásicos Límite: Animals Idioma: En Revista: Carbohydr Polym Año: 2021 Tipo del documento: Article

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