Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels.

Yasuda, Daisuke; Hiraoka, Yoshinori; Ohno, Mikiko; Nishi, Kiyoto; Iwasaki, Hirotaka; Kita, Toru; Nishi, Eiichiro; Kume, Noriaki

Yasuda, Daisuke; Hiraoka, Yoshinori; Ohno, Mikiko; Nishi, Kiyoto; Iwasaki, Hirotaka; Kita, Toru; Nishi, Eiichiro; Kume, Noriaki.

Afiliación

Yasuda D; Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University.
Hiraoka Y; Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University.
Ohno M; Department of Pharmacology, Shiga University of Medical Sciences.
Nishi K; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.
Iwasaki H; Department of Pharmacology, Shiga University of Medical Sciences.
Kita T; Kobe City College of Nursing.
Nishi E; Department of Pharmacology, Shiga University of Medical Sciences.
Kume N; Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University.

Biol Pharm Bull ; 44(3): 363-371, 2021.

Article en En | MEDLINE | ID: mdl-33642545

Asunto(s)

LDL-Colesterol/sangre; Hepatocitos/metabolismo; Hígado/metabolismo; Metaloendopeptidasas/deficiencia; Animales; Células Cultivadas; Masculino; Metaloendopeptidasas/genética; Ratones Transgénicos; Proproteína Convertasa 9/sangre; Receptores de LDL/genética; Receptores de LDL/metabolismo

Palabras clave

cholesterol; inducible degrader of LDL receptor (IDOL); low-density lipoprotein (LDL) receptor; nardilysin; pro-protein convertase subtilisinkexin type 9 (PCSK9)

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Texto completo: 1 Colección: 01-internacional Asunto principal: Metaloendopeptidasas / Hepatocitos / LDL-Colesterol / Hígado Límite: Animals Idioma: En Revista: Biol Pharm Bull Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2021 Tipo del documento: Article

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