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Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.
Tokarew, Jacqueline M; El-Kodsi, Daniel N; Lengacher, Nathalie A; Fehr, Travis K; Nguyen, Angela P; Shutinoski, Bojan; O'Nuallain, Brian; Jin, Ming; Khan, Jasmine M; Ng, Andy C H; Li, Juan; Jiang, Qiubo; Zhang, Mei; Wang, Liqun; Sengupta, Rajib; Barber, Kathryn R; Tran, An; Im, Doo Soon; Callaghan, Steve; Park, David S; Zandee, Stephanie; Dong, Xiajun; Scherzer, Clemens R; Prat, Alexandre; Tsai, Eve C; Takanashi, Masashi; Hattori, Nobutaka; Chan, Jennifer A; Zecca, Luigi; West, Andrew B; Holmgren, Arne; Puente, Lawrence; Shaw, Gary S; Toth, Gergely; Woulfe, John M; Taylor, Peggy; Tomlinson, Julianna J; Schlossmacher, Michael G.
Afiliación
  • Tokarew JM; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • El-Kodsi DN; Graduate Program in Cellular and Molecular Medicine (Neuroscience), Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Lengacher NA; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Fehr TK; Graduate Program in Cellular and Molecular Medicine (Neuroscience), Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Nguyen AP; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Shutinoski B; Graduate Program in Cellular and Molecular Medicine (Neuroscience), Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • O'Nuallain B; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Jin M; Graduate Program in Cellular and Molecular Medicine (Neuroscience), Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Khan JM; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Ng ACH; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Li J; BioLegend Inc., Dedham, MA, USA.
  • Jiang Q; BioLegend Inc., Dedham, MA, USA.
  • Zhang M; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Wang L; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Sengupta R; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Barber KR; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Tran A; Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, ON, Canada.
  • Im DS; BioLegend Inc., Dedham, MA, USA.
  • Callaghan S; Department of Biochemistry, Karolinska Institute, Stockholm, Sweden.
  • Park DS; Amity Institute of Biotechnology, Amity University, Kolkata, West Bengal, 700135, India.
  • Zandee S; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
  • Dong X; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
  • Scherzer CR; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Prat A; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
  • Tsai EC; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Takanashi M; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Hattori N; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
  • Chan JA; Department of Neuroscience, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
  • Zecca L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • West AB; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Holmgren A; Department of Neuroscience, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
  • Puente L; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Shaw GS; Division of Neurosurgery, Department of Surgery, The Ottawa Hospital, Ottawa, ON, Canada.
  • Toth G; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
  • Woulfe JM; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
  • Taylor P; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.
  • Tomlinson JJ; Institute of Biomedical Technologies, Italian National Research Council, Segrate, Milan, Italy.
  • Schlossmacher MG; Department of Neurobiology, Duke University, Durham, NC, USA.
Acta Neuropathol ; 141(5): 725-754, 2021 05.
Article en En | MEDLINE | ID: mdl-33694021
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Texto completo: 1 Colección: 01-internacional Asunto principal: Envejecimiento / Mesencéfalo / Dopamina / Ubiquitina-Proteína Ligasas / Degeneración Nerviosa Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Asunto principal: Envejecimiento / Mesencéfalo / Dopamina / Ubiquitina-Proteína Ligasas / Degeneración Nerviosa Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Año: 2021 Tipo del documento: Article País de afiliación: Canadá