Randomized clinical trial of preoperative skin preparation with 2% chlorhexidine versus conventional hair shaving in percutaneous coronary intervention.
Medicine (Baltimore)
; 100(14): e25304, 2021 Apr 09.
Article
en En
| MEDLINE
| ID: mdl-33832100
ABSTRACT
BACKGROUND:
Preoperative skin preparation is associated with surgical site infection (SSI). Traditional preoperative shaving fails to reduce the risk of SSI. The efficacy of 2% chlorhexidine for preoperative skin preparation in percutaneous coronary intervention (PCI) is sketchy. The aim of this trial was to evaluate whether preoperative skin preparation performed with chlorhexidine was not inferior to a conventional hair removal method.METHODS:
Seventy-eight patients undergoing PCI were randomized into 2 groups of 39 patients, receiving either single sterilization with 2% chlorhexidine or hair shaving respectively between July 2016 and October 2016. The primary endpoints were wound infection rate and bacterial counts. Secondary endpoints were rate of SSI and adverse effects of 2% chlorhexidine.RESULTS:
The results showed that 2% chlorhexidine significantly reduced the colonization of Staphylococcus aureus (Pâ=â.032), S epidermidis (Pâ=â.000), and miscellaneous bacteria (Pâ=â.244) in comparison with hair shaving, respectively. Redness in 24âhours after surgery was observed in 6 patients in the control group (15.4%) and 5 patients (12.8%) in 2% chlorhexidine group. There was no statistically significant difference in SSI rate between 2 skin preparations.CONCLUSION:
In PCI, preoperative skin preparation with 2% chlorhexidine was not inferior to conventional hair shaving in terms of the wound infection rate and SSI rate.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Infección de la Herida Quirúrgica
/
Clorhexidina
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Intervención Coronaria Percutánea
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Remoción del Cabello
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Antiinfecciosos Locales
Tipo de estudio:
Clinical_trials
Límite:
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2021
Tipo del documento:
Article