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First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors.
Falchook, Gerald; Infante, Jeffrey; Arkenau, Hendrik-Tobias; Patel, Manish R; Dean, Emma; Borazanci, Erkut; Brenner, Andrew; Cook, Natalie; Lopez, Juanita; Pant, Shubham; Frankel, Arthur; Schmid, Peter; Moore, Kathleen; McCulloch, William; Grimmer, Katharine; O'Farrell, Marie; Kemble, George; Burris, Howard.
Afiliación
  • Falchook G; Sarah Cannon Research Institute at HealthONE, 1800 Williams St Ste 300, Denver, CO, 80218, United States.
  • Infante J; Tennessee Oncology, 250 25th Ave N #100, Nashville, TN 37203, United States.
  • Arkenau HT; Sarah Cannon Research Institute UK, 93 Harley St., Marylebone, London W1G 6AD, United Kingdom.
  • Patel MR; Florida Cancer Specialists and Research Institute, 600 N Cattleman Rd, Ste 200, Sarasota, FL 34232, United States.
  • Dean E; Sarah Cannon Research Institute, 1100 Martin L. King Jr. Boulevard, Nashville, TN 37203 United States.
  • Borazanci E; Christie Hospital - Clinical Oncology, The Christie NHS Foundation Trust, Clinical Oncology Department, Wilmslow Road, Manchester, M20 4BX, United Kingdom.
  • Brenner A; Scottsdale Healthcare Research Institute, 10510 North 92nd Street, Suite 200, Scottsdale, AZ 85258, United States.
  • Cook N; CTRC at The University of Texas Health Center, 7979 Wurzbach Rd., San Antonio, TX 78229, United States.
  • Lopez J; Christie Hospital - Clinical Oncology, The Christie NHS Foundation Trust, Clinical, Oncology Department, Wilmslow Road, Manchester, M20 4BX, United Kingdom.
  • Pant S; Division of Cancer Sciences, University of Manchester, Oxford Rd, Manchester, M13 9PL, United Kingdom.
  • Frankel A; Royal Marsden Hospital, Downs Road, Sutton, SM25PT, United Kingdom.
  • Schmid P; University of Oklahoma Health Sciences, 800 NE 10 Street, 5th Floor, Oklahoma City, OK 73104, United States.
  • Moore K; UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, United States.
  • McCulloch W; St Bartholomew's Hospital, West Smithfield, London, EC1A7BE, United Kingdom.
  • Grimmer K; University of Oklahoma Health Sciences, 800 NE 10 Street, 5th Floor, Oklahoma City, OK 73104, United States.
  • O'Farrell M; Sagimet Biosciences Inc., 155 Bovet Rd., San Mateo, CA 94402, United States.
  • Kemble G; Sagimet Biosciences Inc., 155 Bovet Rd., San Mateo, CA 94402, United States.
  • Burris H; Sagimet Biosciences Inc., 155 Bovet Rd., San Mateo, CA 94402, United States.
EClinicalMedicine ; 34: 100797, 2021 Apr.
Article en En | MEDLINE | ID: mdl-33870151
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Texto completo: 1 Colección: 01-internacional Tipo de estudio: Prognostic_studies Idioma: En Revista: EClinicalMedicine Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Tipo de estudio: Prognostic_studies Idioma: En Revista: EClinicalMedicine Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos