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NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate.
D'Angelo, Luigi; Astro, Elisa; De Luise, Monica; Kurelac, Ivana; Umesh-Ganesh, Nikkitha; Ding, Shujing; Fearnley, Ian M; Gasparre, Giuseppe; Zeviani, Massimo; Porcelli, Anna Maria; Fernandez-Vizarra, Erika; Iommarini, Luisa.
Afiliación
  • D'Angelo L; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, 40126 Bologna, Italy.
  • Astro E; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, 40126 Bologna, Italy.
  • De Luise M; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
  • Kurelac I; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
  • Umesh-Ganesh N; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
  • Ding S; Medical Research Council-Mitochondrial Biology Unit, University of Cambridge, CB2 0XY Cambridge, UK.
  • Fearnley IM; Medical Research Council-Mitochondrial Biology Unit, University of Cambridge, CB2 0XY Cambridge, UK.
  • Gasparre G; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy; Center for Applied Biomedical Research (CRBA), University of Bologna, 40138 Bologna, Italy.
  • Zeviani M; Medical Research Council-Mitochondrial Biology Unit, University of Cambridge, CB2 0XY Cambridge, UK; Venetian Institute of Molecular Medicine, 35128 Padua, Italy; Department of Neurosciences, University of Padua, 35128 Padua, Italy.
  • Porcelli AM; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, 40126 Bologna, Italy; Interdepartmental Center of Industrial Research (CIRI) Life Science and Health Technologies, University of Bologna, 40064 Ozzano dell'Emilia, Italy.
  • Fernandez-Vizarra E; Medical Research Council-Mitochondrial Biology Unit, University of Cambridge, CB2 0XY Cambridge, UK; Institute of Molecular, Cell and Systems Biology, University of Glasgow, G12 8QQ Glasgow, UK. Electronic address: erika.fernandez-vizarra@glasgow.ac.uk.
  • Iommarini L; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, 40126 Bologna, Italy. Electronic address: luisa.iommarini2@unibo.it.
Cell Rep ; 35(3): 109002, 2021 04 20.
Article en En | MEDLINE | ID: mdl-33882309

Texto completo: 1 Colección: 01-internacional Asunto principal: Atrofia Óptica / Complejo I de Transporte de Electrón / Proteínas de la Membrana / Mitocondrias / NADH Deshidrogenasa Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Asunto principal: Atrofia Óptica / Complejo I de Transporte de Electrón / Proteínas de la Membrana / Mitocondrias / NADH Deshidrogenasa Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Italia