Bufalin inhibits peritoneal dissemination of gastric cancer through endothelial nitric oxide synthase-mitogen-activated protein kinases signaling pathway.

Zou, Dan; Song, Jincheng; Deng, Mingming; Ma, Yanju; Yang, Chunjiao; Liu, Jiaqing; Wang, Song; Wen, Zhenpeng; Tang, Yu; Qu, Xiujuan; Zhang, Ye

Zou, Dan; Song, Jincheng; Deng, Mingming; Ma, Yanju; Yang, Chunjiao; Liu, Jiaqing; Wang, Song; Wen, Zhenpeng; Tang, Yu; Qu, Xiujuan; Zhang, Ye.

Afiliación

Zou D; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Song J; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Deng M; Department of Oncology, the Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Ma Y; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yang C; Department of Medical Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Insititute, Shenyang, China.
Liu J; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Wang S; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Wen Z; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Tang Y; The First Laboratory of Cancer Institute, the First Hospital of China Medical University, Shenyang, China.
Qu X; Department of Medical Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Insititute, Shenyang, China.
Zhang Y; Department of Medical Oncology, the First Hospital of China Medical University, Shenyang, China.

FASEB J ; 35(5): e21601, 2021 05.

Article en En | MEDLINE | ID: mdl-33913201

Asunto(s)

Biomarcadores de Tumor/metabolismo; Bufanólidos/farmacología; Regulación Neoplásica de la Expresión Génica; Proteínas Quinasas Activadas por Mitógenos/metabolismo; Óxido Nítrico Sintasa de Tipo III/metabolismo; Neoplasias Peritoneales/tratamiento farmacológico; Neoplasias Gástricas/tratamiento farmacológico; Animales; Antineoplásicos/farmacología; Apoptosis; Biomarcadores de Tumor/genética; Proliferación Celular; Femenino; Humanos; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Proteínas Quinasas Activadas por Mitógenos/genética; Óxido Nítrico Sintasa de Tipo III/genética; Neoplasias Peritoneales/genética; Neoplasias Peritoneales/metabolismo; Neoplasias Peritoneales/secundario; Transducción de Señal; Neoplasias Gástricas/genética; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patología; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

MAPK; NOS3; bufalin; gastric cancer; peritoneal dissemination

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Peritoneales / Neoplasias Gástricas / Bufanólidos / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Proteínas Quinasas Activadas por Mitógenos / Óxido Nítrico Sintasa de Tipo III Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China

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