Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates.

Bosák, Juraj; Lexa, Matej; Fiedorová, Kristýna; Gadara, Darshak C; Micenková, Lenka; Spacil, Zdenek; Litzman, Jirí; Freiberger, Tomás; Smajs, David

Bosák, Juraj; Lexa, Matej; Fiedorová, Kristýna; Gadara, Darshak C; Micenková, Lenka; Spacil, Zdenek; Litzman, Jirí; Freiberger, Tomás; Smajs, David.

Afiliación

Bosák J; Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czechia.
Lexa M; Faculty of Informatics, Masaryk University, Brno, Czechia.
Fiedorová K; Centre for Cardiovascular Surgery and Transplantation, Brno, Czechia.
Gadara DC; Department of Clinical Immunology and Allergology, Faculty of Medicine, Masaryk University, Brno, Czechia.
Micenková L; RECETOX Center, Faculty of Science, Masaryk University, Brno, Czechia.
Spacil Z; RECETOX Center, Faculty of Science, Masaryk University, Brno, Czechia.
Litzman J; RECETOX Center, Faculty of Science, Masaryk University, Brno, Czechia.
Freiberger T; Department of Clinical Immunology and Allergology, Faculty of Medicine, Masaryk University, Brno, Czechia.
Smajs D; Department of Clinical Immunology and Allergology, St. Anne's University Hospital in Brno, Brno, Czechia.

Front Immunol ; 12: 671239, 2021.

Article en En | MEDLINE | ID: mdl-34054845

Asunto(s)

Clostridiaceae/fisiología; Inmunodeficiencia Variable Común/microbiología; Biología Computacional/métodos; Disbiosis/microbiología; Microbioma Gastrointestinal/genética; ARN Ribosómico 16S/genética; Adenosina/metabolismo; Biodiversidad; Inmunodeficiencia Variable Común/genética; Disbiosis/genética; Heces/microbiología; Homeostasis; Humanos; Metabolómica; Metagenoma

Palabras clave

CVID; Hungatella hathewayi; common variable immunodeficiency; metabolome; metagenome; microbiome

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Texto completo: 1 Colección: 01-internacional Asunto principal: ARN Ribosómico 16S / Inmunodeficiencia Variable Común / Biología Computacional / Disbiosis / Microbioma Gastrointestinal / Clostridiaceae Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Front Immunol Año: 2021 Tipo del documento: Article

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