Elevated USP9X drives early-to-late-stage oral tumorigenesis via stabilisation of anti-apoptotic MCL-1 protein and impacts outcome in oral cancers.

Sulkshane, Prasad; Pawar, Sagar N; Waghole, Rohit; Pawar, Sushil S; Rajput, Priyanka; Uthale, Abhay; Oak, Swapnil; Kalkar, Prajakta; Wani, Harshada; Patil, Rahul; Nair, Sudhir; Rane, Pallavi; Teni, Tanuja

Sulkshane, Prasad; Pawar, Sagar N; Waghole, Rohit; Pawar, Sushil S; Rajput, Priyanka; Uthale, Abhay; Oak, Swapnil; Kalkar, Prajakta; Wani, Harshada; Patil, Rahul; Nair, Sudhir; Rane, Pallavi; Teni, Tanuja.

Afiliación

Sulkshane P; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Pawar SN; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India.
Waghole R; Glickman Lab, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Pawar SS; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Rajput P; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Uthale A; KBH Dental College and Hospital, Panchwati, Nashik, Maharashtra, India.
Oak S; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Kalkar P; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Wani H; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India.
Patil R; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Nair S; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India.
Rane P; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.
Teni T; Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre (TMC), Kharghar, Navi Mumbai, Maharashtra, India.

Br J Cancer ; 125(4): 547-560, 2021 08.

Article en En | MEDLINE | ID: mdl-34079080

Asunto(s)

Carcinoma de Células Escamosas/patología; Neoplasias de la Boca/patología; Proteína 1 de la Secuencia de Leucemia de Células Mieloides/química; Ubiquitina Tiolesterasa/metabolismo; Regulación hacia Arriba; Animales; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Línea Celular Tumoral; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Ratones; Neoplasias de la Boca/genética; Neoplasias de la Boca/metabolismo; Proteína 1 de la Secuencia de Leucemia de Células Mieloides/metabolismo; Estadificación de Neoplasias; Trasplante de Neoplasias; Pronóstico; Estabilidad Proteica; Análisis de Supervivencia; Ubiquitina Tiolesterasa/genética; Ubiquitinación

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas / Regulación hacia Arriba / Ubiquitina Tiolesterasa / Proteína 1 de la Secuencia de Leucemia de Células Mieloides Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Año: 2021 Tipo del documento: Article País de afiliación: India

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