Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation.

Sasaki, So-Ichiro; Zhang, Di; Iwabuchi, Sadahiro; Tanabe, Yamato; Hashimoto, Shinichi; Yamauchi, Akira; Hayashi, Katsuhiro; Tsuchiya, Hiroyuki; Hayakawa, Yoshihiro; Baba, Tomohisa; Mukaida, Naofumi

Sasaki, So-Ichiro; Zhang, Di; Iwabuchi, Sadahiro; Tanabe, Yamato; Hashimoto, Shinichi; Yamauchi, Akira; Hayashi, Katsuhiro; Tsuchiya, Hiroyuki; Hayakawa, Yoshihiro; Baba, Tomohisa; Mukaida, Naofumi.

Afiliación

Sasaki SI; Cancer Research Institute, Division of Molecular Bioregulation, Kanazawa University, Ishikawa, Japan.
Zhang D; Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Iwabuchi S; Cancer Research Institute, Division of Molecular Bioregulation, Kanazawa University, Ishikawa, Japan.
Tanabe Y; Institute of Advanced Medicine, Department of Molecular Pathophysiology, Wakayama Medical University, Wakayama, Japan.
Hashimoto S; Cancer Research Institute, Division of Molecular Bioregulation, Kanazawa University, Ishikawa, Japan.
Yamauchi A; Institute of Advanced Medicine, Department of Molecular Pathophysiology, Wakayama Medical University, Wakayama, Japan.
Hayashi K; Tazuke Kofukai Medical Research Institute, Department of Breast Surgery, Osaka, Japan.
Tsuchiya H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
Hayakawa Y; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
Baba T; Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Mukaida N; Cancer Research Institute, Division of Molecular Bioregulation, Kanazawa University, Ishikawa, Japan.

Cancer Sci ; 112(12): 4883-4893, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34632664

Asunto(s)

Neoplasias Óseas/genética; Regulación Neoplásica de la Expresión Génica; Neoplasias Mamarias Experimentales/genética; Receptores Acoplados a Proteínas G/genética; Animales; Neoplasias Óseas/metabolismo; Neoplasias Óseas/secundario; Línea Celular Tumoral; Proliferación Celular/genética; Colágeno Tipo III/metabolismo; Femenino; Eliminación de Gen; Humanos; Neoplasias Mamarias Experimentales/metabolismo; Neoplasias Mamarias Experimentales/patología; Ratones Endogámicos BALB C; Ratones SCID; Unión Proteica; Receptores Acoplados a Proteínas G/metabolismo; Carga Tumoral/genética

Palabras clave

GPR56/ADGRG1; bone metastasis; fibroblast; mouse; triple-negative breast cancer

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Óseas / Regulación Neoplásica de la Expresión Génica / Receptores Acoplados a Proteínas G / Neoplasias Mamarias Experimentales Límite: Animals / Female / Humans Idioma: En Revista: Cancer Sci Año: 2021 Tipo del documento: Article País de afiliación: Japón

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