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Consensus on diagnosis and management of Cushing's disease: a guideline update.
Fleseriu, Maria; Auchus, Richard; Bancos, Irina; Ben-Shlomo, Anat; Bertherat, Jerome; Biermasz, Nienke R; Boguszewski, Cesar L; Bronstein, Marcello D; Buchfelder, Michael; Carmichael, John D; Casanueva, Felipe F; Castinetti, Frederic; Chanson, Philippe; Findling, James; Gadelha, Mônica; Geer, Eliza B; Giustina, Andrea; Grossman, Ashley; Gurnell, Mark; Ho, Ken; Ioachimescu, Adriana G; Kaiser, Ursula B; Karavitaki, Niki; Katznelson, Laurence; Kelly, Daniel F; Lacroix, André; McCormack, Ann; Melmed, Shlomo; Molitch, Mark; Mortini, Pietro; Newell-Price, John; Nieman, Lynnette; Pereira, Alberto M; Petersenn, Stephan; Pivonello, Rosario; Raff, Hershel; Reincke, Martin; Salvatori, Roberto; Scaroni, Carla; Shimon, Ilan; Stratakis, Constantine A; Swearingen, Brooke; Tabarin, Antoine; Takahashi, Yutaka; Theodoropoulou, Marily; Tsagarakis, Stylianos; Valassi, Elena; Varlamov, Elena V; Vila, Greisa; Wass, John.
Afiliación
  • Fleseriu M; Oregon Health & Science University, Portland, OR, USA. Electronic address: fleseriu@ohsu.edu.
  • Auchus R; University of Michigan, Ann Arbor, MI, USA.
  • Bancos I; Mayo Clinic, Rochester, MN, USA.
  • Ben-Shlomo A; Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Bertherat J; Université de Paris, Assistance Publique-Hôpitaux de Paris, Centre de Référence Maladies Rares de la Surrénale, Service d'Endocrinologie, Hôpital Cochin, Paris, France.
  • Biermasz NR; Leiden University Medical Center and European Reference Center for Rare Endocrine Conditions (Endo-ERN), Leiden, Netherlands.
  • Boguszewski CL; Federal University of Parana, Curitiba, Brazil.
  • Bronstein MD; University of Sao Paulo, Sao Paulo, Brazil.
  • Buchfelder M; University Hospital Erlangen, Erlangen, Germany.
  • Carmichael JD; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Casanueva FF; Santiago de Compostela University and Ciber OBN, Santiago de Compostela, Spain.
  • Castinetti F; Aix Marseille Université, Marseille Medical Genetics, INSERM, Marseille, France; Assistance Publique Hopitaux de Marseille, Marseille, France; Department of Endocrinology, La Conception Hospital, Marseille, France.
  • Chanson P; Université Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
  • Findling J; Medical College of Wisconsin, Milwaukee, WI, USA.
  • Gadelha M; Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
  • Geer EB; Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Giustina A; San Raffaele Vita-Salute University, Milan, Italy.
  • Grossman A; University of London, London, UK; University of Oxford, Oxford, UK.
  • Gurnell M; University of Cambridge, Cambridge, UK; NIHR Cambridge Biomedical Research Center, Cambridge, UK; Addenbrooke's Hospital, Cambridge, UK.
  • Ho K; The Garvan Institute of Medical Research, Sydney, NSW, Australia.
  • Ioachimescu AG; Emory University School of Medicine, Atlanta, GA, USA.
  • Kaiser UB; Brigham & Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
  • Karavitaki N; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK; Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals B
  • Katznelson L; Stanford University, Stanford, CA, USA.
  • Kelly DF; Pacific Neuroscience Institute, Santa Monica, CA, USA.
  • Lacroix A; Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
  • McCormack A; The Garvan Institute of Medical Research, Sydney, NSW, Australia.
  • Melmed S; Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Molitch M; Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Mortini P; San Raffaele Vita-Salute University, Milan, Italy.
  • Newell-Price J; University of Sheffield, Sheffield, UK.
  • Nieman L; National Institutes of Health, Bethesda, MD, USA.
  • Pereira AM; Leiden University Medical Center and European Reference Center for Rare Endocrine Conditions (Endo-ERN), Leiden, Netherlands.
  • Petersenn S; ENDOC Center for Endocrine Tumors, Hamburg, Germany and University of Duisburg-Essen, Essen, Germany.
  • Pivonello R; Università Federico II di Napoli, Naples, Italy.
  • Raff H; Medical College of Wisconsin, Milwaukee, WI, USA; Advocate Aurora Research Institute, Aurora St. Luke's Medical Center, Milwaukee, WI, USA.
  • Reincke M; Department of Medicine IV, University Hospital of LMU, Ludwig-Maximilians-Universität, Munich, Germany.
  • Salvatori R; Johns Hopkins University, Baltimore, MD, USA.
  • Scaroni C; University of Padova, Padova, Italy.
  • Shimon I; Rabin Medical Center, Beilinson Hospital, Petah-Tikva, Israel.
  • Stratakis CA; National Institutes of Health, Bethesda, MD, USA.
  • Swearingen B; Massachusetts General Hospital, Boston, MA, USA.
  • Tabarin A; CHU de Bordeaux, Hôpital Haut Lévêque, University of Bordeaux, Bordeaux, France.
  • Takahashi Y; Nara Medical University, Kashihara, Japan.
  • Theodoropoulou M; Department of Medicine IV, University Hospital of LMU, Ludwig-Maximilians-Universität, Munich, Germany.
  • Tsagarakis S; Evangelismos Hospital, Athens, Greece.
  • Valassi E; Endocrinology Unit, Hospital General de Catalunya, Barcelona, Spain; Research Center for Pituitary Diseases (CIBERER Unit 747), Hospital Sant Pau, Barcelona, Spain.
  • Varlamov EV; Oregon Health & Science University, Portland, OR, USA.
  • Vila G; Medical University of Vienna, Vienna, Austria.
  • Wass J; Churchill Hospital, Oxford, United Kingdom.
Lancet Diabetes Endocrinol ; 9(12): 847-875, 2021 12.
Article en En | MEDLINE | ID: mdl-34687601
ABSTRACT
Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term management to optimise patient outcomes. The Pituitary Society convened a consensus workshop comprising more than 50 academic researchers and clinical experts to discuss the application of recent evidence to clinical practice. In advance of the virtual meeting, data from 2015 to present about screening and diagnosis; surgery, medical, and radiation therapy; and disease-related and treatment-related complications of Cushing's disease summarised in recorded lectures were reviewed by all participants. During the meeting, concise summaries of the recorded lectures were presented, followed by small group breakout discussions. Consensus opinions from each group were collated into a draft document, which was reviewed and approved by all participants. Recommendations regarding use of laboratory tests, imaging, and treatment options are presented, along with algorithms for diagnosis of Cushing's syndrome and management of Cushing's disease. Topics considered most important to address in future research are also identified.
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Texto completo: 1 Colección: 01-internacional Asunto principal: Síndrome de Cushing / Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT) Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Lancet Diabetes Endocrinol Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Síndrome de Cushing / Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT) Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Lancet Diabetes Endocrinol Año: 2021 Tipo del documento: Article